financial support from the National Natural Science Foundation of China(No.32072445);the Science and Technology Plan Project of Guizhou Province(Qiankehezhicheng[2024]the general 083);the Program of Introducing Talents to Chinese Universities(No.D20023);the Central Government Guides Local Science and Technology Development Fund Projects(Qiankehezhongyindi(2023)001);the Technology Achievement Transformation(general project)of Guizhou Province(Qiankehechengguo[2022]the general 063);Key Agricultural Technology R&D Projects of the Xinjiang Production and Construction Corps(NYHXGG,No.2023AA602);the Frontiers Science Centre for Asymmetric Synthesis and Medicinal Molecules;Department of Education;Guizhou Province[Qianjiaohe KY(2020)004];the specific research fund of TheInnovation Platform for Academicians of Hainan Province(No.SQ2020PTZ0009)。
Piperidine is a crucial pharmacophore and a special scaffold in the realm of drug discovery.Its flexibility increases the molecule’s capability to bind to the receptor.The piperidine-containing compounds are distingu...
the National Natural Science Foundation of China(Nos.22371141,22221002);National Key R&D Program of China(No.2021YFA1500200);Natural Science Foundation of Tianjin(No.20JCJQJC00030);Haihe Laboratory of Sustainable Chemical Transformations(No.ZYT202101);Frontiers Science Center for New Organic Matter at Nankai University(No.63181206);Tencent Foundation for financial support.
Herein,a method for the enantioselective reduction of unprotected 2-alkylpyridines is reported for the first time.By using pinacolborane and an amide as reducing agents,a large number of 2-alkylpiperidines were synthe...
Supported by Undergraduate Innovation and Entrepreneurship Training Program of Suzhou University in 2024(Synthesis and Application of Novel Thiazole Fluorescent Probes);Key Project of Natural Science Research in Colleges and Universities of Department of Education of Anhui Province(KJ2021A1109).
[Objectives]This study was conducted to investigate the effects of piperidine derivatives on the proliferation and apoptosis of tumor cells(Hele).[Methods]The target end product(piperidine derivative)was synthesized t...
The authors gratefully acknowledge the financial support of this work by Natural Science Foundation of China(grant no 22075031);Jilin Provincial Science&Technology Department(grant no 20220201105GX)。
Research on anion exchange membrane fuel cells(AEMFCs)mainly focuses on the membrane module,and improving its performance has always been the focus of researchers.To create high-performance anion exchange membranes(AE...
the financial support from the National Natural Science Foundation of China(No.21808059);the Fundamental Research Funds for the Central Universities(No.JKA01221712).
N-formylation of amines,a class of synthetically important reactions,is typically conducted using metal catalysts that are relatively expensive or not readily available and usually needs harsh conditions to increase t...
financially supported by the National Natural Science Foundation of China (No. 81872775)。
The rapid prevalence of antibiotic resistance has led to a significant global health problem. Although colistin is the last resort antibiotic, it is limited by dose dependent toxicity. A critical approach to solve thi...
supported by the Natural Science Foundation of Guizhou Education University(Nos.14BS017 and 2019ZD001);the Natural Science Foundation of Guizhou Province(No.QKHPTRC20185778-09)。
Nitro and amino groups were introduced into piperidine skeleton to design derivatives of piperidine(labeled asα,β1,β2,β3,γandδ).Heats of formation(HOFs)are calculated in detail at the B3PW91/6-311+G(d,p)level fo...
the National Key Research and Development Program of China(Grant No.2017YFB0702800);China Postdoctoral Science Foundation(2016M600347).
Hierarchical ZSM-5 zeolite with radial mesopores is controllably synthesized using piperidine in a NaOH solution.The piperidine molecules enter the zeolite micropores and protect the zeolite framework from extensive d...
Financially supported by the National Natural Science Foundation of China(No.21571094,21661021,21865015);the Graduate Student Creativity Funding of Jiangxi Province(No.YC2015-S008)
Reactions of piperidine derivatives 4-(aminomethyl)piperidine(4-AMPD) and 1-methylpiperidin-4-amine(1-MPDA) with semi-conductive metal iodine SbI3 and PbI2 in concentrated HI aqueous solution afforded two one-dimensio...
supported by the Research Grants Council General Research Fund (No. 17301314)
Furans bearing epoxy enolsilane units via a tether that incorporates a nitrogen heteroatom,undergo intramolecular(4+3)cycloadditions to generate bis-heteroatomic polycyclic adducts having piperidine moieties in their ...