甲氨蝶呤治疗眼内淋巴瘤1例  

Methotrexate therapy for primary intraocular lymphoma:a case report

作　　者：王勤 曾凤[1] 魏聪 Wang Qin;Zeng Feng;Wei Cong(Department of Ophthalmology,Qingyuan Hospital Affiliated to Guangzhou Medical University(Qingyuan People′s Hospital),Qingyuan 511518,China)

机构地区：[1]广州医科大学附属清远医院(清远市人民医院)眼科,清远511518

出　　处：《中华眼科杂志》2025年第1期61-64,共4页Chinese Journal of Ophthalmology

摘　　要：1例63岁因无明显诱因左眼视力下降4个月伴右眼视物模糊的男性患者,首次就诊广州医科大学附属清远医院眼科,诊断为双眼葡萄膜炎;随后在脑科诊断为中枢神经系统淋巴瘤,并行全身治疗;患者因双眼视力下降进行性加重,再次就诊于眼科,根据玻璃体液细胞因子检测等结果,诊断为双眼眼内淋巴瘤,行双眼玻璃体腔甲氨蝶呤注射术8次,双眼视力得到有效提高。A 63‑year‑old male patient presented with a four‑month history of vision loss in the left eye and blurred vision in the right eye,the cause of which was not immediately apparent.The patient was initially diagnosed with uveitis in both eyes at the Department of Ophthalmology.Subsequently,the patient was diagnosed as central nervous system lymphoma at the Department of Brain Medicine and initiated a systemic treatment.However,due to the progressive deterioration of visual function,a further evaluation was performed at the Department of Ophthalmology.Based on the results of the vitreous fluid cytokine test,intraocular lymphoma was diagnosed in both eyes.Intravitreal methotrexate injections were administered for eight times and a notable improvement in visual acuity was achieved in both eyes.

关 键 词：眼内淋巴瘤 甲氨蝶呤 玻璃体内注射 

分 类 号：R739.7[医药卫生—肿瘤]