局部晚期喉癌术后放疗患者预后的影响因素分析  

Analysis of influencing factors of prognosis in patients with locally advanced laryngeal cancer undergoing postoperative radiotherapy

作　　者：康敏礼 吕安定 曾汶 KANG Minli;LYU Anding;ZENG Wen(Third Department of Radiotherapy,Ganzhou Cancer Hospital,Ganzhou 341000,Jiangxi,China;Department of Oncology,Chongyi County People’s Hospital of Jiangxi Province,Ganzhou 341300,Jiangxi,China;Department of Head and Neck Surgery,Ganzhou Cancer Hospital,Ganzhou 341000,Jiangxi,China)

机构地区：[1]赣州市肿瘤医院放疗三科,江西赣州341000 [2]江西省崇义县人民医院肿瘤科,江西赣州341300 [3]赣州市肿瘤医院头颈外科,江西赣州341000

出　　处：《癌症进展》2024年第24期2680-2682,共3页Oncology Progress

基　　金：江西省自然科学基金(20181BAB205037)。

摘　　要：目的探讨局部晚期喉癌术后放疗患者预后的影响因素。方法选取52例局部晚期喉癌手术患者,术后均进行放疗并随访1年。根据随访结果将患者分为复发组和未复发组,比较两组患者的临床特征,采用Logistic回归模型分析局部晚期喉癌术后放疗患者预后的影响因素。结果52例局部晚期喉癌患者中,20例(38.46%)患者出现复发,32例(61.54%)患者未出现复发。单因素分析结果显示,复发组和未复发组患者的性别、年龄、淋巴结转移情况比较,差异均有统计学意义(P﹤0.05)。多因素Logistic回归分析结果显示,男性、年龄≥65岁、淋巴结转移均是局部晚期喉癌术后放疗患者预后的独立危险因素(P﹤0.05)。结论局部晚期喉癌术后放疗患者仍存在复发风险,男性、年龄≥65岁、淋巴结转移均是局部晚期喉癌术后放疗患者预后的独立危险因素。Objective To investigate the influencing factors of prognosis in patients with locally advanced laryngeal cancer undergoing postoperative radiotherapy.Method A total of 52 patients with locally advanced laryngeal cancer who received surgery were selected,all patients underwent postoperative radiotherapy and followed up for 1 year.Accord-ing to the follow-up results,the patients were divided into recurrence group and non-recurrence group.The clinical char-acteristics of the two groups were compared,and the influencing factors of prognosis in patients with local advanced la-ryngeal cancer undergoing postoperative radiotherapy were analyzed by Logistic regression model.Result Among 52 patients with locally advanced laryngeal cancer,20 patients(38.46%)had recurrence,and 32 patients(61.54%)did not.Univariate analysis showed that there were significant differences in gender,age and lymph node metastasis between the recurrence group and the non-recurrence group(P<0.05).Multivariate Logistic regression analysis showed that male,age≥65 years old,and lymph node metastasis were independent risk factors for prognosis in patients with locally ad-vanced laryngeal cancer undergoing postoperative radiotherapy.Conclusion Patients with locally advanced laryngeal cancer undergoing postoperative radiotherapy still have the risk of recurrence.Male,age≥65 years old,and lymph node metastasis are independent risk factors for prognosis in patients with locally advanced laryngeal cancer undergoing post-operative radiotherapy.

关 键 词：局部晚期喉癌 术后放疗 预后 影响因素 

分 类 号：R739.65[医药卫生—肿瘤]