Compensation or Preservation?Diferent Roles of Functional Lateralization in Speech Perception of Older Non‑musicians and Musicians  

作　　者：Xinhu Jin Lei Zhang Guowei Wu Xiuyi Wang Yi Du 

机构地区：[1]Institute of Psychology,Chinese Academy of Sciences,Beijing 100101,China [2]Department of Psychology,University of Chinese Academy of Sciences,Beijing 100049,China [3]CAS Center for Excellence in Brain Science and Intelligence Technology,Shanghai 200031,China [4]Chinese Institute for Brain Research,Beijing 102206,China

出　　处：《Neuroscience Bulletin》2024年第12期1843-1857,共15页神经科学通报(英文版)

基　　金：supported by STI 2030-Major Projects(2021ZD0201500);the National Natural Science Foundation of China(31822024,31671172,and 32300881);the Strategic Priority Research Program of Chinese Academy of Sciences(XDB32010300);the Scientifc Foundation of Institute of Psychology,Chinese Academy of Sciences(E1CX172005 and E1CX4725CX).

摘　　要：Musical training can counteract age-related decline in speech perception in noisy environments.However,it remains unclear whether older non-musicians and musicians rely on functional compensation or functional preservation to counteract the adverse efects of aging.This study utilized resting-state functional connectivity(FC)to investigate functional lateralization,a fundamental organization feature,in older musicians(OM),older non-musicians(ONM),and young non-musicians(YNM).Results showed that OM outperformed ONM and achieved comparable performance to YNM in speech-in-noise and speech-in-speech tasks.ONM exhibited reduced lateralization than YNM in lateralization index(LI)of intrahemispheric FC(LI_intra)in the cingulo-opercular network(CON)and LI of interhemispheric heterotopic FC(LI_he)in the language network(LAN).Conversely,OM showed higher neural alignment to YNM(i.e.,a more similar lateralization pattern)compared to ONM in CON,LAN,frontoparietal network(FPN),dorsal attention network(DAN),and default mode network(DMN),indicating preservation of youth-like lateralization patterns due to musical experience.Furthermore,in ONM,stronger left-lateralized and lower alignment-to-young of LI_intra in the somatomotor network(SMN)and DAN and LI_he in DMN correlated with better speech performance,indicating a functional compensation mechanism.In contrast,stronger right-lateralized LI_intra in FPN and DAN and higher alignment-to-young of LI_he in LAN correlated with better performance in OM,suggesting a functional preservation mechanism.These fndings highlight the diferential roles of functional preservation and compensation of lateralization in speech perception in noise among elderly individuals with and without musical expertise,ofering insights into successful aging theories from the lens of functional lateralization and speech perception.

关 键 词：Functional lateralization Speech perception AGING Musical training experience 

分 类 号：R395.1[哲学宗教—心理学]