Single-Nucleus Transcriptomic Taxonomy of Multiple Sevoflurane-Induced Cell Type Specificity in the Hippocampus of Juvenile Non-human Primates  

作　　者：Yanyong Cheng Xiao Chen Jia Yan Lei Zhang Hong Jiang 

机构地区：[1]Department of Anesthesiology,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,200011,China

出　　处：《Neuroscience Bulletin》2024年第12期1943-1949,共7页神经科学通报(英文版)

基　　金：supported by the National Natural Science Foundation of China(82201321,82171173,and 82071177);the Science and Technology Commission of Shanghai Municipality(22YF1422500);the Shanghai Ninth People’s Hospital(JYZP001).

摘　　要：Dear Editor,The widespread and growing use of anesthesia in children makes its safety a major health issue of interest.Mounting evidence suggests that anesthetic exposure during early development may result in neurological changes in young children and animals.Sevoflurane,the most commonly used inhaled anesthetic in children,leads to visual recognition memory impairment,anxiety behaviors,and myelination deficits in infant rhesus macaques[1-3].

关 键 词：ANESTHESIA IMPAIRMENT Mount 

分 类 号：R338.24[医药卫生—人体生理学]