OCT测量脉络膜厚度在学龄儿童近视进展中的研究  

Research on Choroidal Thickness Measured by OCT in the Progression of Myopia in School-aged Children

作　　者：张海燕[1] 李洪霞 单石蕾[1] 刘宏伟 Zhang Hai-yan;Li Hong-xia;Shan Shi-lei(Jiamusi University Affiliated First Hospital,Jiamusi 154000,China)

机构地区：[1]佳木斯大学,154000 [2]杭州爱尔眼科医院 [3]佳木斯大学第一附属医院

出　　处：《中国斜视与小儿眼科杂志》2024年第4期24-24,I0001,25,26,共4页Chinese Journal of Strabismus & Pediatric Ophthalmology

基　　金：佳木斯大学博士科研课题(JMSUBZ202006)。

摘　　要：目的研究学龄儿童不同屈光状态脉络膜厚度(SFCT)与眼部生物学参数的关系。方法回顾性队列观察研究,收集2023年1月至2024年6月7~15岁学龄儿童89例(178眼),按等效球镜(SE)分为3组:近视前期组;轻度近视组和中、高度近视组。应用频域光学相干断层(SD-OCT)测量黄斑中心凹下脉络膜厚度(SFCT)变化情况,并分析不同组脉络膜厚度与眼部生物学参数的相关性以及随时间变化规律。结果SFCT与SE在轻度近视组与中高度近视组中呈显著正相关(P<0.05),SFCT与K以及AL/CR在轻度近视组中呈显著负相关(P<0.05)。SFCT与AL为负相关关系。SFCT与ACD在中高度近视组中呈显著正相关(P<0.05)。在基线、第3个月、第6个月、第9个月与第12个月进行3组比较,SFCT均存在显著差异(P<0.05),轻度近视组和中高度近视组与近视前期组比明显下降(P<0.05),中高度近视组与轻度近视组比明显下降(P<0.05)结论近视度数越高,SFCT越薄,且SFCT与K、AL、AL/CR以及ACD均具有相关性,随着随访时间的增加,SFCT逐渐变薄。Objective To investigate the relationship between SFCT and ocular biometric parameters in school-aged children with different refractive states.Methods A retrospective cohort observational study was conducted.We collected data from 89 school-aged children(178 eyes)aged 7 to 15 years from January 2023 to June 2024.The children were divided into three groups based on their SE:pre-myopia group,mild myopia group,and moderate-to-high myopia group.SD-OCT was used to measure the changes in SFCT.The correlation between SFCT and ocular biometric parameters was analyzed for different groups.Results SFCT was significantly positively correlated with SE in the mild myopia group and the moderate-to-high myopia group(P<0.05).SFCT was significantly negatively correlated with corneal curvature(K)and axial length/corneal radius(AL/CR)in the mild myopia group(P<0.05).SFCT was negatively correlated with axial length(AL).SFCT was significantly positively correlated with anterior chamber depth(ACD)in the moderate-tohigh myopia group(P<0.05).Conclusion As the degree of myopia increases,SFCT becomes thinner,and SFCT is correlated with K,AL,AL/CR,and ACD.

关 键 词：学龄儿童 近视前期 等效球镜 脉络膜厚度 

分 类 号：G63[文化科学—教育学]