免疫肠内营养剂在胃癌根治术后辅助化疗期间的应用价值  

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作  者:张斌斌 孙元水[2] 

机构地区:[1]杭州市第九人民医院,311225 [2]浙江省立同德医院,311200

出  处:《浙江临床医学》2025年第1期72-73,76,共3页Zhejiang Clinical Medical Journal

摘  要:目的 探讨免疫肠内营养剂应用于胃癌根治术后辅助化疗期间的疗效和安全性。方法 选取2017年1月至2022年6月收治的胃癌术后行化疗患者63例,采用随机法分为观察组(n=32)和对照组(n=31),对照组予常规化疗方案,观察组在对照组基础上予免疫肠内营养剂治疗。比较两组患者化疗前后营养状况、生活质量、化疗完成率、炎症反应。结果 两组患者化疗后Karnofsky功能状态及EORTC QLQ-C30生活质量量表评分、白蛋白、体质量、预后营养指数、化疗完成率以及炎症反应发生率比较,差异有统计学意义(P<0.05)。结论 在胃癌根治术后辅助化疗期间使用免疫肠内营养剂可以改善患者的营养状况和生活质量,降低化疗反应。Objective To explore the efficacy and safety of immunoenteric nutrition agent applied during adjuvant chemotherapy after radical surgery for gastric cancer.Methods 63 cases of postoperative chemotherapy patients with gastric cancer admitted from January 2017 to June 2022 were selected and divided into the observation group(n=32)and the control group(n=31)by randomisation method.The control group was given conventional chemotherapy regimen,while the observation group was given immunoenteric nutrient treatment based on the control group.Compared the nutritional status,quality of life,chemotherapy completion rate and inflammatory response of the two groups before and after chemotherapy.Results The Karnofsky functional status and EORTC QLQ-C30 quality of life scale scores,albumin,body weight,prognostic nutritional index,chemotherapy completion rate,and incidence of inflammatory reaction were compared between the two groups after chemotherapy,the difference was statistically significant(P<0.05).Conclusion The use of immune enteral nutrition during adjuvant chemotherapy after radical gastric cancer treatment can improve the nutritional status and quality of life of patients,improve the completion rate of chemotherapy,and reduce inflammatory reactions,which is worthy of being promoted and applied in the clinic.

关 键 词:胃癌 手术 化疗 肠内营养 

分 类 号:R735.2[医药卫生—肿瘤] R459.3[医药卫生—临床医学]

 

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