3D-SWE联合S-Detect技术诊断甲状腺良恶性结节价值观察  

Value of 3D-SWE combined with S-Detect technology in diagnosis of benign and malignant thyroid nodules

作　　者：崔娜 董磊 CUI Na;DONG Lei(Department of Ultrasound Diagnosis,960 Hospital of Joint Logistics Support Force of the Chinese People’s Liberation Army,Jinan 250031,Shandong,China)

机构地区：[1]中国人民解放军联勤保障部队第九六〇医院超声诊断科,山东济南250031

出　　处：《生物医学工程与临床》2025年第1期53-58,共6页Biomedical Engineering and Clinical Medicine

摘　　要：目的探究三维剪切波弹性成像(3D-SWE)联合超声人工智能辅助诊断技术(简称S-Detect技术)诊断甲状腺良恶性结节的价值。方法选择2021年6月至2022年6月在中国人民解放军联勤保障部队第九六〇医院治疗并行超声检查的甲状腺结节患者97例(97个病灶),其中男性19例,女性78例;年龄27~65岁,平均年龄50.08岁(标准差7.19岁);结节最大径5~25 mm,平均最大径10.87 mm(标准差3.75 mm);根据病理诊断结果将患者分为良性组和恶性组。测量两组横断面、矢状面和冠状面最大弹性值(Emax)、平均弹性值(Emean);以病理诊断结果为“金标准”,分析3DSWE、S-Detect技术及其联合应用诊断甲状腺良恶性结节的价值。结果97例甲状腺结节患者病理诊断共检出良性结节54例(良性组),恶性结节43例(恶性组)。恶性组横断面、矢状面和冠状面的Emax均明显大于良性组[(72.65±18.31)kPa vs(29.45±9.17)kPa,(75.29±20.53)kPa vs(36.83±11.47)kPa,(79.26±21.48)kPa vs(33.53±9.84)kPa],Emean均明显大于良性组[(55.29±14.64)kPa vs(25.56±8.43)kPa,(56.35±15.23)kPa vs(31.25±9.86)kPa,(60.65±17.69)kPa vs(28.42±9.15)kPa],差异均有统计学意义(P<0.05)。取最佳临界值时,矢状面Emax诊断甲状腺良恶性结节的诊断效能最佳,曲线下面积(AUC)为0.834(P<0.05)。以矢状面Emax≥49.40 kPa为诊断标准,3D-SWE诊断、SDetect技术诊断及其联合诊断的AUC分别为0.826、0.803、0.875(P<0.001),与病理诊断一致性较高(Kappa值=0.661、0.604、0.749);3D-SWE联合S-Detect技术诊断的特异度高于S-Detect技术(88.89%vs 81.48%),差异有统计学意义(P<0.05)。结论3D-SWE检查、S-Detect技术诊断甲状腺良恶性结节均具有一定应用价值,与病理诊断一致性较高;二者联合应用可提高S-Detect技术辅助诊断的特异度。Objective To explore the value of three-dimensional shear wave elastography(3D-SWE)combined with ultrasound artificial intelligence-assisted diagnostic technology(S-Detect technology)in diagnosis of benign and malignant thyroid nodules.Methods From June 2021 to June 2022,a total of 97 patients with thyroid nodules(97 lesions)who performed ultrasound examination were enrolled,which included 19 males and 78 females,aged 27-65 years old with mean age of 50.08 years old(standard deviation 7.19 years old);maximum diameter of nodules was 5-25 mm with mean maximum diameter of 10.87 mm(standard deviation 3.75 mm).According to pathological examination results,all of them were divided into benign group and malignant group.The maximum elasticity value(Emax)and mean elasticity value(Emean)of transverse,sagittal and coronal planes of 2 groups were measured.The diagnostic value of 3D-SWE,S-Detect technology and combined method in benign and malignant thyroid nodules were analyzed,and pathological diagnosis was set as the“gold standard”.Results A total of 54 cases of benign nodules(benign group)and 43 of malignant nodules(malignant group)were detected by pathological diagnosis in 97 patients with thyroid nodules.The Emax of the transverse,sagittal and coronal planes in malignant group was statistically significantly higher than that in benign group[(72.65±18.31)kPa vs(29.45±9.17)kPa,(75.29±20.53)kPa vs(36.83±11.47)kPa,(79.26±21.48)kPa vs(33.53±9.84)kPa](P<0.05),Emean was significantly higher in malignant group than in benign group[(55.29±14.64)kPa vs(25.56±8.43)kPa,(56.35±15.23)kPa vs(31.25±9.86)kPa,(60.65±17.69)kPa vs(28.42±9.15)kPa](P<0.05).When taken the optimal critical value,sagittal Emax displayed the best diagnostic efficacy in diagnosis of benign and malignant thyroid nodules,and area under the curve(AUC)was 0.834(P<0.05).Taken sagittal Emax≥49.40 kPa as diagnostic standard,the AUC value of 3D-SWE,S-Detect and combined diagnosis were 0.826,0.803 and 0.875,respectively(P<0.001),which were highly consist

关 键 词：甲状腺结节 超声检查 三维剪切波弹性成像 超声人工智能辅助诊断技术 诊断 

分 类 号：R730.41[医药卫生—肿瘤] R736.1[医药卫生—临床医学]