2003—2021年天津市北辰区结直肠癌死亡率及疾病负担趋势分析  

Analysis on trend of mortality and disease burden for colorectal cancer from 2003 to 2021 in Beichen district of Tianjin

作　　者：李晓娜[1] 张婕 王德征[2] LI Xiaona;ZHANG Jie;WANG Dezheng(Department of Infectious Disease Control,Beichen District Center for Disease Control and Prevention,Tianjin 300400,China;不详)

机构地区：[1]天津市北辰区疾病预防控制中心传染病控制科,天津300400 [2]天津市疾病预防控制中心非传染病预防控制所,天津300011

出　　处：《中国慢性病预防与控制》2024年第12期905-909,共5页Chinese Journal of Prevention and Control of Chronic Diseases

摘　　要：目的了解2003—2021年天津市北辰区居民结直肠癌(CRC)死亡率及其变化趋势,为CRC的预防控制提供依据。方法利用2003—2021年天津市全死因监测管理系统得到北辰区居民全死因监测数据,采用SPSS 11.5软件计算CRC死亡率、早死所致寿命损失年(YLL)率、伤残所致寿命损失年(YLD)率和伤残调整寿命年(DALY)率,率的比较采用χ^(2)检验。采用Segi's世界标准人口构成进行标化,采用Joinpoint回归分析CRC死亡率和疾病负担指标的变化趋势,计算年度变化百分比(APC)。结果2003—2021年天津市北辰区CRC标化死亡率由2.54/10万上升至7.13/10万,上升趋势有统计学意义(APC=4.11%,P<0.01)。2003—2021年,<50、50~59岁年龄组CRC死亡率变化趋势无统计学意义(P>0.01),60岁及以上年龄组CRC死亡率呈上升趋势(P<0.05,P<0.01)。2003—2021年,男性居民CRC标化死亡率由2.85/10万上升至9.75/10万,上升趋势有统计学意义(APC=5.39%,P<0.01),女性居民CRC标化死亡率由2.22/10万上升至4.51/10万,上升趋势无统计学意义(APC=2.22%,P>0.05)。2003—2021年,男性CRC标化死亡率总体高于女性,差异有统计学意义(Z=2.78,P<0.01)。2003—2021年天津市北辰区CRC标化DALY率由79.86/10万上升至186.15/10万,上升趋势有统计学意义(APC=3.02%,P<0.01);男性居民CRC标化DALY率由113.43/10万上升至262.51/10万,上升趋势有统计学意义(APC=3.87%,P<0.01),女性居民CRC标化DALY率由46.29/10万上升至109.76/10万,上升趋势无统计学意义(APC=1.87%,P>0.05)。2003—2021年,男性CRC标化DALY率总体高于女性(Z=16.21,P<0.01)。2003—2021年北辰区居民CRC的DALY以YLL为主,占比从2003年的97.25%下降至2021年的94.79%。结论2003—2021年天津市北辰区居民CRC死亡率和疾病负担明显上升。应重点关注男性、老年人群,加强CRC的防治,减少CRC死亡与疾病负担。Objective To understand the mortality and change trends of colorectal cancer(CRC)in Beichen district of Tianjin from 2003 to 2021,and provide the basis for the prevention and control of CRC.Methods The monitoring management system of whole cause of death in Tianjin from 2003 to 2021 was used to obtain the monitoring data of whole cause of death in Beichen district.The CRC mortality,years of life loss(YLL),years of life loss due to disability(YLD),and disability-adjusted life years(DALY)were calculated.The χ^(2) test was used to compare the rates,the used software was SPSS 11.5.Segi's world standard population composition was used for calibration,Joinpoint regression was used to analyze the change trends of mortality and disease burden of CRC,and to calculate the annual percentage change(APC).Results From 2003 to 2021,the CRC standardized mortality rate in Beichen district of Tianjin increased from 2.54/105 to 7.13/105 from 2003 to 2021(APC=4.11%,P<0.01).From 2003 to 2021,there was no significant trend in CRC mortality in the<50 and 50-59 years old groups(P>0.05),and CRC mortality in the≥60 years old group increased significantly(P<0.01).From 2003 to 2021,the CRC standardized mortality rate of male residents increased from 2.85/105 to 9.75/105 with a statistically significant trend(APC=5.39%,P<0.01),and the CRC standardized mortality rate of female residents increased from 2.22/105 to 4.51/105 without significant trend(APC=2.22%,P>0.05).From 2003 to 2021,the CRC standardized mortality rate in males was significantly higher than that in females(Z=2.78,P<0.01).From 2003 to 2021,the CRC standardized DALY rate in Beichen district of Tianjin increased from 79.86/105 to 186.15/105 with significant upward trend(APC=3.02%,P<0.01);the CRC standardized DALY rate of male residents increased from 113.43/105 to 262.51/105 with significant upward trend(APC=3.87%,P<0.01);the CRC standardized DALY rate of female residents increased from 46.29/105 to 109.76/105 without significant upward trend(APC=1.87%,P>0.05).From 2003 to 202

关 键 词：结直肠癌 死亡率 早死所致寿命损失年 伤残所致寿命损失年 伤残调整寿命年 

分 类 号：R735.34[医药卫生—肿瘤] R181.3[医药卫生—临床医学]