大承气汤加减保留灌肠联合刮痧治疗肠梗阻患者的效果  

Effects of modified Dachengqi decoction retention enema combined with scraping in treatment of patients with intestinal obstruction

作　　者：冯璐 卜鑫燕 FENG Lu;BU Xinyan(Qingzhou Hospital of Traditional Chinese MedicineDepartment of Spleen and Stomach Diseases,Weifang 262500 Shandong,China;Qingzhou Hospital of Traditional Chinese Medicine,Department of Rehabilitation Medicine,Weifang 262500 Shandong,China)

机构地区：[1]青州市中医院脾胃病科,山东潍坊262500 [2]青州市中医院康复医学科,山东潍坊262500

出　　处：《中国民康医学》2025年第3期120-123,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:观察大承气汤加减保留灌肠联合刮痧治疗肠梗阻患者的效果。方法:回顾性分析2021年10月至2023年10月该院收治的90例肠梗阻患者的临床资料,根据治疗方案不同将其分为对照组和观察组各45例。对照组采用刮痧治疗,观察组在对照组基础上联合大承气汤加减保留灌肠治疗。比较两组临床疗效、临床症状改善时间,治疗前后炎性因子[C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)]水平、胃肠激素[血管活性肠肽(VIP)、胃泌素(GAS)、胃动素(MTL)]水平,以及不良反应发生率。结论:观察组治疗总有效率为86.67%(39/45),高于对照组的62.22%(28/45),差异有统计学意义(P<0.05);观察组腹痛消失时间、腹胀消失时间、首次排气时间、首次排便时间、肠鸣音恢复时间均短于对照组,差异有统计学意义(P<0.05);两组CRP、TNF-α、IL-6水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);两组VIP、GAS、MTL水平均高于治疗前,且观察组高于观察组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结果:大承气汤加减保留灌肠联合刮痧治疗肠梗阻患者可提高治疗总有效率和胃肠激素水平,缩短临床症状改善时间,以及降低炎性因子水平的效果优于单纯刮痧治疗。Objective:To observe effects of modified Dachengqi decoction retention enema combined with scraping in treatment of patients with intestinal obstruction.Methods:The clinical data of 90 patients with intestinal obstruction admitted to the Hospital of traditional Chinese medicine from October 2021 to October 2023 were retrospectively analyzed.According to different treatment options,they were divided into control group and observation group,45 cases in each group.The control group was treated with scraping therapy,while the observation group was treated with modified Dachengqi decoction retention enema on the basis of that of the control group.The clinical efficacy,the improvement time of clinical symptoms,the levels of inflammatory factors[C-reactive protein(CRP),tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)]and the levels of gastrointestinal hormones[vasoactive intestinal peptide(VIP),gastrin(GAS),motilin(MTL)]before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the observation group was 86.67%(39/45),which was higher than 62.22%(28/45)in the control group,and the difference was statistically significant(P<0.05).The disappearance time of abdominal pain,the disappearance time of abdominal distension,the first exhaust time,the first defecation time and the recovery time of bowel sounds in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of CRP,TNF-αand IL-6 in the two groups were lower than those before the treatment,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of VIP,GAS and MTL in the two groups were higher than those before the treatment,those in the observation group were higher than those in the observation group,and the differences were statistically significant(P<0.05).However

关 键 词：大承气汤加减 保留灌肠 刮痧 肠梗阻 炎性因子 胃肠激素 临床症状 

分 类 号：R574.2[医药卫生—消化系统]