国内外川崎病指南的异同点解读  

Interpretation of similarities and differences in Kawasaki disease guidelines at home and abroad

作　　者：潘炎[1] 谢利剑 焦富勇[3] PAN Yan;XIE Li-Jian;JIAO Fu-Yong(Children's Hospital of Shaanxi Provincial People's Hospital/Diagnosis and Treatment Center of Kawasaki Disease of Shaanxi Province,Xi'an 710068,China)

机构地区：[1]长江大学附属第一医院儿科,湖北荆州434000 [2]复旦大学附属金山医院儿科,上海201508 [3]陕西省人民医院儿童病院/陕西省川崎病诊疗中心,陕西西安710068

出　　处：《中国当代儿科杂志》2025年第2期144-147,共4页Chinese Journal of Contemporary Pediatrics

基　　金：湖北省儿科医疗联盟课题(HPAMRP202117);上海金山区医学重点专科项目(JSZK2023A04)。

摘　　要：该文综合比较了PubMed数据库中检索到的来自中国、阿根廷、欧洲、意大利、日本、西班牙和美国这7个国家/地区的川崎病(Kawasaki disease,KD)指南,分析了它们在KD诊断和治疗方面的异同。结果显示,所有指南均一致推荐单次输注免疫球蛋白2 g/kg作为KD的一线治疗方案,并且均不主张将甲泼尼龙或泼尼松单独作为KD的常规一线治疗药物。然而,在KD的分类、诊断标准以及具体治疗方法等方面,各指南之间存在一定的差异。鉴于此,未来有必要进一步加强国际指南制订的合作,并开展多中心临床研究,以期达成更高层次的专家共识,从而推动KD诊治水平的全面提升。This paper comprehensively compares the Kawasaki disease(KD)guidelines from seven countries/regions,including China,Argentina,Europe,Italy,Japan,Spain,and the United States,as retrieved from the PubMed database.It analyzes the similarities and differences in KD diagnosis and treatment among these guidelines.The results show that all guidelines consistently recommend a single infusion of immunoglobulin at a dosage of 2 g/kg as the firstline treatment for KD,and none advocate for the routine use of methylprednisolone or prednisone as standalone first-line treatment options for KD.However,there are some differences among the guidelines regarding classification,diagnostic criteria,and specific treatment methods for KD.Therefore,it is essential to further strengthen international collaboration in guideline development and conduct multicenter clinical research in the future,aiming to achieve a higher level of expert consensus,thereby promoting the enhancement of KD diagnosis and treatment.

关 键 词：川崎病 诊断 治疗 指南 解读 儿童 

分 类 号：R73[医药卫生—肿瘤]