高压氧治疗散发性脑炎28例疗效观察  

USE OF HYPERBARIC OXYGEN FOR DIFFUSE ENCEPHALITIS:EXPERIENCE WITH 28 CONSECUTIVE CASES

作　　者：付汝林[1] 魏孝英 高国英 Fu Rulin(Division of Hyperbaric Oxygen Chamber Department of Medicine)

机构地区：[1]泸州医学院附属医院高压氧室

出　　处：《泸州医学院学报》1985年第1期54-57,共4页Journal of Luzhou Medical College

摘　　要：本文报告用高压氧加一般内科疗法治疗散发性脑炎28例的结果,有效率为96.5%,其中治愈率为78.6%。一般内科治疗的有效率为89.3%,治愈率为46.4%。高压氧治疗的治愈率显著高于一般内科疗法(P<0.05)。高压氧治疗的时机越早越好,病程一月内者治愈率可达90%,而病程30—60天者治愈率仅为50%。高压氧能促使意识尽快恢复,神经功能的改善,主要是通过提高动脉血的氧分压,血氧的含量,增加氧的弥散半径,降低颅内压。因此,我们提倡散发性脑炎应及早行高压氧治疗。The paper reported the results of 28 patients with diffuse encephalitis treated in hyperbaric oxygen chamber.The overall effective rate of combined routine medical therapy and hyperbaric oxygen was 96.5%,and the cure rate of all patients was 78.5%,compared with 83.9,46.4%of medical therapy alone,respectively.It is obvious that the hyperbaric oxygen combined with routine medical therapy is significantly superior to the medical therapy alone(P<0.05).In order to get the best results,the hyperbaric oxygen therapy should be instituted as early as possible.In this series,the cure rate of those treated by the hyperbaric therapy was 90%when patients were in the early stage(30 days);while in the late stage,ranging from 30 to 60 days,it decreased to 50%.A major advantage of hyperbaric oxygen is to help a patient revive from coma and further improve the function of brain.Also,it can increase the Pa Oand oxygen level in the arterial blood,and enhance the oxygen diffusion in the capillary.Therefore,decrease of high intracranial pressure may be expected.Based on these findings,we concluded that hyperbaric oxygen is a safe,effective adjunct to the treatment of patients with diffuse encephalitis.In order to achieve best results,it should be instituted as early as possible.

关 键 词：内科疗法 高压氧治疗 散发性脑炎 内科治疗 越早越好 神经功能 氧分压 治愈率 

分 类 号：R74[医药卫生—神经病学与精神病学]