2015-2024年国家自然科学基金临床药理学领域申请与资助项目分析  

Analysis of application and funded projects of National Natural Science Foundation of China in Clinical Pharmacology from 2015 to 2024

作　　者：郑楠 刘悦 韩立炜[1] ZHENG Nan;LIU Yue;HAN Li-wei(Department of Health Sciences,National Natural Science Foundation of China,Bejing 100085,China;Beijing Key Laboratory of Mental Disorders,National Clinical Research Center for Mental Disorders&National Center for Mental Disorders,Bejing Anding Hospital,CapitalMedical University,Beijing 100088,China;Schoolof Pharmacy,NingxiaMedicalUl niversity,Yinchuan 750004,1Ningxia Hui Autonomous Region,China)

机构地区：[1]国家自然科学基金委员会医学科学部,北京100085 [2]首都医科大学附属北京安定医院国家精神心理疾病临床医学研究中心,精神疾病诊断与治疗北京市重点实验室,北京100088 [3]宁夏医科大学药学院,宁夏回族自治区银川750004

出　　处：《中国临床药理学杂志》2025年第2期151-158,共8页The Chinese Journal of Clinical Pharmacology

摘　　要：目的对2015-2024年国家自然科学基金临床药理学领域申请与资助项目进行分析,旨在为临床药理学项目的申报提供一定的参考。方法在国家自然科学基金管理信息系统中收集2015-2024年“临床药理(H3511)”代码下的申请与资助项目信息,包括资助年度、项目名称、项目类别、资助金额、关键词、研究方向等,据此建立数据库并进行统计分析。结果2015-2024年临床药理领域接收面上、青年科学基金、地区科学基金项目申请2031项,资助320项,累计资助直接经费11848万元,资助项目数量和金额呈波动上升趋势。申请项目所研究病种主要集中在恶性肿瘤、心脑血管疾病、神经精神疾病、代谢性疾病等。申请和获资助项目研究方向主要集中在个体化用药、临床药物不良反应与毒性、临床生物标志物,分别占申请和获资助项目总数的67.6%与70.3%。结论随着新理论、新方法和新技术的不断涌现,临床药理学科得到了快速发展,临床药理学领域基础研究日益受到关注,国家自然科学基金一直重视对该领域的支持,但该领域申请项目也存在临床特色有待加强、疾病种类和研究方向冷热不均、学科内发展不均衡等问题,有待临床药理学研究者加强关注。Objective To analyze the application and funded projects inthe field of clinical pharmacology supported by the National NaturalScience Foundation of China(NSFC)from 2015 to 2024,aiming toprovide a reference for the application.Methods Information on theapplication and funded projects under the"Clinical Pharmacology(H3511)"code from 2015 to 2024 was collected from the NSFCmanagement information system,including funding year,project name,project category,funding amount,keywords,research directions,etc.Adatabase was established based on this information for statistical analysis.Results From 2015 to 2024,2031 applications were received forgeneral,young scientist,and regional scientist foundation in the clinicalpharmacology research field,with 320 projects funded,accumulating adirect funding of 118.48 million yuan.The number and amount of fundedprojects showed a fluctuating upward trend.The diseases studied in theapplications were mainly concentrated in malignant tumors,cardiovascularand cerebrovascular diseases,neuropsychiatric diseases,and metabolicdiseases.The research directions of the applications and funded projects were mainly focused on personalized medication,drug adverse reactions and toxicity,and clinical biomarkers,accounting for 67.6%and 70.3%of the total number of application and funded projects,respectively.Conclusion With the emergence of new methods and technologies,clinical pharmacology has developed rapidly,andbasic research in this field has increasingly attracted attention.The NSFC has always emphasized support for this field.However,there are still some issues of the applications,such as the need to strengthen clinical characteristics,unevendistribution of disease types and research directions,and unbalanced development within the discipline,which requireincreased attention from clinical pharmacology researchers.

关 键 词：临床药理学 国家自然科学基金 申请与资助项目 

分 类 号：R969[医药卫生—药理学]