Exploration of the immunologic characteristics of KIT/PDGFRA wild-type gastrointestinal stromal tumor and potential application of neoantigen vaccination  

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作  者:Yishan Li Qin Wang Lin Li Shaohua Yuan Hui Chen Rutian Li Fangcen Liu 

机构地区:[1]The Comprehensive Cancer Center of Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing,Jiangsu 210008,China [2]Clinical Cancer Institute of Nanjing University,Nanjing,Jiangsu 210008,China [3]Department of Pathology,Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing,Jiangsu 210008,China [4]OrigiMed,Shanghai 201114,China

出  处:《Chinese Medical Journal》2024年第21期2627-2629,共3页中华医学杂志(英文版)

基  金:supported by the Natural Science Foundation of China(Nos.82203178,82272852,and 82103687);Jiangsu Provincial Key Research and Development Program(No.BE2020619);Natural Science Foundation of Jiangsu Province(No.BK20220191);Nanjing Medical Science and Technology Development Foundation(No.YKK22086).

摘  要:To the Editor:Gastrointestinal stromal tumors(GISTs)are the most common mesenchymal tumors of the gastrointestinal tract.GISTs mostly occur in the stomach or small intestine among patients around 40-60 years of age,and are insensitive to chemotherapy or radiotherapy.

关 键 词:gastrointestinal STOMACH INTESTINE 

分 类 号:R73[医药卫生—肿瘤]

 

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