Trend of gastrointestinal and liver diseases in China:Results of the Global Burden of Disease Study,2019  

作　　者：Xiaowei Tang Ping Wang Shu Huang Jieyu Peng Wei Zhang Xiaomin Shi Lei Shi Xiaolin Zhong Muhan Lyu Xian Zhou Enqiang Linghu 

机构地区：[1]Department of Gastroenterology,The First Medical Center of Chinese PLA General Hospital,Beijing 100853,China [2]Department of Gastroenterology,The Affiliated Hospital of Southwest Medical University,Luzhou,Sichuan 646000,China [3]Department of Nuclear Medicine,Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province,Luzhou,Sichuan 646000,China [4]Department of Gastroenterology,Lianshui County People’s Hospital,Huaian,Jiangsu 210004,China [5]Department of Gastroenterology,Lianshui People’s Hospital of Kangda College Affiliated to Nanjing Medical University,Huaian,Jiangsu 210004,China

出　　处：《Chinese Medical Journal》2024年第19期2358-2368,共11页中华医学杂志(英文版)

基　　金：supported by a grant from Natural Science Foundation of Sichuan Province(No.2022NSFSC1378)。

摘　　要：Background:China is one of the countries with the largest burden of gastrointestinal and liver diseases(GILD)in the world.The GILD constitutes various causes of mortality and disability.The study aimed to investigate the trend of GILD in China using the Global Burden of Diseases Study 2019(GBD 2019)data resources from 1990 to 2019.Methods:The data on the age-standardized mortality rates(ASMR)and disability-adjusted life years(DALYs)for GILD in China from 1990 to 2019 were collected from the GBD 2019 data resources.Furthermore,the ranking of the main causes of deaths and DALYs,as well as the trends of ASMR,DALYs,years of life lost(YLLs),and years of life lost due to disability(YLDs)per 1,000,000 in GILD were reported.Results:The ASMR and DALYs for stomach cancer,liver cancer,and esophageal cancer,which ranked top three among the GILDs from 1990 to 2019,were gradually decreasing.Significant decreases in the ASMR and DALYs were found in diarrheal diseases and acute hepatitis(A,E,and C).However,noteworthy increases were found in those of colon and rectum cancer(CRC)and pancreatic cancer.Trend of DALYs,mortality,and YLLs rates for most of GILD were decreasing from 1990 to 2019,except the burden of CRC and pancreatic cancer with an increasing trend.The DALYs,mortality and YLLs of most GILD diseases showed decreasing trends from 1990 to 2019,except the burden of CRC and pancreatic cancer with an increasing trends.Conclusions:The result of the GBD 2019 showed that the rates of most GILDs decreased in China;however,gastrointestinal and liver cancer,such as stomach cancer still held the top ranking.Furthermore,the shift from infectious diseases to non-communicable causes among GILD burden is occurring.

关 键 词：Gastrointestinal diseases Liver diseases Global Burden of Disease MORTALITY Disability-adjusted life years China 

分 类 号：R73[医药卫生—肿瘤]