Impairment of pulmonary microvascular endothelial cells:The ground for COPD?  

作　　者：Hui Qi Yunlong Hou Ningxin Han Peipei Jin Jing Guo Tongxing Wang Zhenhua Jia 

机构地区：[1]Hebei Academy of Integrated Traditional Chinese and Western Medicine,Shijiazhuang,Hebei 050091,China [2]State Key Laboratory for Innovation and Transformation of Luobing Theory,Shijiazhuang,Hebei 050035,China [3]High-Level TCM Key Disciplines of National Administration of Traditional Chinese Medicine-Luobing Theory,Shijiazhuang,Hebei 050035,China [4]Graduate School,Hebei Medical University,Shijiazhuang,Hebei 050017,China [5]Graduate School,Hebei University of Chinese Medicine,Shijiazhuang,Hebei 050090,China [6]Hebei Yiling Hospital,Shijiazhuang,Hebei 050090,China

出　　处：《Chinese Medical Journal》2024年第19期2369-2371,共3页中华医学杂志(英文版)

基　　金：supported by the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTD-D-202206);the Key Project of National Natural Science Foundation of China(No.82130123);the Natural Science Foundation of Hebei Province(Nos.H2023106039 and H2021106032);the S&T Program of Hebei(Nos.E2020100001 and 23372508D);the National Natural Science Foundation for Youth Project(No.82205319);the Scientific Research Project of Hebei Provincial Administration of Traditional Chinese Medicine(No.2024401).

摘　　要：To the Editor:Chronic obstructive pulmonary disease(COPD)is a heterogeneous lung condition characterized by abnormalities in the airways(bronchitis and bronchiolitis)and alveoli(emphysema),as well as pulmonary inflammation,leading to persistent and progressive airflow obstruction.[1]Pulmonary microvascular endothelial cells(PMECs),the main component of pulmonary microvasculature,accounts for about 23%of the human lung cells.PMECs play a pivotal role in the progression of COPD by maintaining lung homeostasis and being involved in various pathogenic processes.

关 键 词：LUNG HOMEOSTASIS MICROVASCULAR 

分 类 号：R56[医药卫生—呼吸系统]