重复经颅磁刺激联合综合康复训练对老年痴呆患者认知功能的影响  

Effects of Repeated Transcranial Magnetic Stimulation Combined with Comprehensive Rehabilitation Training on Cognitive Function in Senile Dementia Patients

作　　者：屈江华 孙新同 QU Jianghua;SUN Xintong(Department of Traditional Chinese Medicine,The 960th Hospital of the Chinese People's Liberation Army Joint Logistic Support Force,Jinan 250031,China;Department of Neurosurgery,The 960th Hospital of the Chinese People's Liberation Army Joint Logistic Support Force,Jinan 250031,China)

机构地区：[1]中国人民解放军联勤保障部队第九六〇医院中医科,山东济南250031 [2]中国人民解放军联勤保障部队第九六〇医院神经外科,山东济南250031

出　　处：《反射疗法与康复医学》2024年第20期47-50,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的探讨重复经颅磁刺激(rTMS)联合综合康复训练对老年痴呆患者认知功能的影响。方法选取2022年6月—2023年5月中国人民解放军联勤保障部队第九六〇医院收治的80例老年痴呆患者为研究对象,按照随机数字表法将其分为对照组和观察组,各40例。两组患者均给予常规干预,对照组采用rTMS干预,观察组在对照组的基础上联合综合康复训练干预。比较两组患者的认知功能、痴呆严重程度及日常生活能力。结果干预前,两组蒙特利认知评估量表(MoCA)、简易智能状态量表(MMSE)及日常生活能力量表(ADL)评分比较,组间差异无统计学意义(P>0.05);干预后,观察组MoCA各个维度评分及总分均高于对照组,组间差异有统计学意义(P<0.05);观察组MMSE、ADL评分分别为(22.93±1.13)分、(64.14±7.23)分,均高于对照组的(18.37±2.25)分、(48.93±7.73)分,组间差异有统计学意义(P<0.05)。结论采用r TMS联合综合康复训练干预在老年痴呆患者中,可有助于促进患者认知功能提升,缓解痴呆症状,并提升患者日常生活能力。Objective To explore the effects of repetitive transcranial magnetic stimulation(rTMS)combined with comprehensive rehabilitation training on cognitive function in senile dementia patients.Methods A total of 80 patients with senile dementia admitted to the 960th Hospital of the Chinese People's Liberation Army Joint Logistic Support Force from June 2022 to May 2023 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 40 cases in each group.Patients in both groups were given routine intervention,the control group was given rTMS intervention,and the observation group was combined with comprehensive rehabilitation training intervention on the basis of the control group.The cognitive function,dementia severity and daily living ability of patients in the two groups were compared.Results Before intervention,there were no significant differences in the scores of Monterey Cognitive Assessment Scale(MoCA),Mini-Mental State Examination(MMSE)and Activities of Daily Living Scale(ADL)between the two groups(P>0.05).After intervention,MoCA scores and total scores of observation group were higher than those of the control group,and the differences between the groups were statistically significant(P<0.05);MMSE and ADL scores in the observation group were(22.93±1.13)points and(64.14±7.23)points,respectively,which were higher than(18.37±2.25)points and(48.93±7.73)points in the control group,and the differences between the groups were statistically significant(P<0.05).Conclusion The use of rTMS combined with comprehensive rehabilitation training to intervene in senile dementia patients can help promote the improvement of cognitive function,alleviate of dementia symptoms,and improve patients'activities of daily living.

关 键 词：老年痴呆 重复经颅磁刺激 综合康复训练 认知功能 日常生活能力 

分 类 号：R749.16[医药卫生—神经病学与精神病学]