荧光胸腔镜肺段切除术治疗早期非小细胞肺癌的临床效果  

Clinical effect of fluorescence thoracoscopic segmentectomy in the treatment of early non-small cell lung cancer

作　　者：李逢昌[1] 曹健斌[1] 李富骊 何凌云[1] 林世红[1] LI Fengchang;CAO Jianbin;LI Fuli;HE Lingyun;LIN Shihong(Department of Thoracic Surgery,Liuzhou People's Hospital Affiliated to Guangxi Medical University,Liuzhou,Guangxi 545006,China)

机构地区：[1]广西医科大学附属柳州市人民医院胸外科,广西柳州545006

出　　处：《医药前沿》2025年第4期51-54,共4页Journal of Frontiers of Medicine

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题(Z20210028)。

摘　　要：目的探讨荧光胸腔镜肺段切除术治疗早期非小细胞肺癌(NSCLC)的临床效果。方法选取2017年1月—2023年1月于广西医科大学附属柳州市人民医院胸外科行手术治疗的早期NSCLC患者120例,根据手术方法不同分为观察组和对照组,各60例。对照组行胸腔镜肺萎陷法肺段切除术,观察组行荧光胸腔镜肺段切除术,比较两组患者围手术期指标、不同时间第1秒用力呼气容积(FEV_(1))、术后并发症发生情况和随访3个月治疗效果。结果观察组手术时间、胸管留置时间和术后住院时间短于对照组,术中出血量和胸腔引流量少于对照组,差异有统计学意义(P<0.05)。两组术前、出院前和术后3、6、12个月FEV_(1)比较,差异无统计学意义(P>0.05);两组术后并发症总发生率比较,差异无统计学意义(P>0.05);随访3个月,观察组治疗总有效率略高于对照组,但两组比较差异无统计学意义(P>0.05)。结论荧光胸腔镜肺段切除术作为一种新型手术方式,在治疗早期NSCLC方面展现出显著优势,可减少患者手术创伤和痛苦,加速术后恢复,且不会过多影响患者肺功能和增加并发症发生风险。Objective To investigate the clinical effect of fluorescence thoracoscopic segmentectomy in the treatment of early non-small cell lung cancer(NSCLC).Methods A total of 120 patients with early NSCLC who underwent surgical treatment in the Department of Thoracic Surgery of Liuzhou People's Hospital Affiliated to Guangxi Medical University from January 2017 to January 2023 were selected and divided into observation group and control group according to different surgical methods,with 60 cases in each group.The control group underwent thoracoscopic pulmonary collapse segmentectomy,and the observation group underwent fluorescence thoracoscopic segmentectomy.The perioperative indicators,forced expiratory volume in one second(FEV_(1))at different time periods,postoperative complications and therapeutic effect after 3 months of follow-up were compared between the two groups.Results The operation time,chest tube indwelling time and postoperative hospital stay in the observation group were shorter than those in the control group,and the intraoperative blood loss and thoracic drainage volume were less than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in FEV_(1) between the two groups before operation,before discharge and 3,6 and 12 months after operation(P>0.05).There was no significant difference in the total incidence of postoperative complications between the two groups(P>0.05).After 3 months of follow-up,the total effective rate of treatment in the observation group was slightly higher than that in the control group,but there was no significant difference between the two groups(P>0.05).Conclusions As a new surgical method,fluorescence thoracoscopic segmentectomy shows significant advantages in the treatment of early NSCLC,which can reduce the surgical trauma and pain of patients,accelerate postoperative recovery,and will not affect the lung function of patients too much and increase the risk of complications.

关 键 词：肿瘤 非小细胞肺癌 早期 荧光 吲哚菁绿 胸腔镜 肺段切除术 第1秒用力呼气容积 

分 类 号：R734[医药卫生—肿瘤]