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作 者:彭兴辉 Peng Xing-hui(Department of Anesthesiology,The First People's Hospital of Wolong District,Nanyang 473000,Henan,China)
机构地区:[1]河南省南阳市卧龙区第一人民医院麻醉科,河南南阳473000
出 处:《四川生理科学杂志》2025年第1期189-192,共4页
摘 要:目的:探讨超声引导肋横突孔阻滞复合全身麻醉在乳腺癌根治术患者中的应用效果。方法:回顾性分析医院2022年1月-2023年1月收治的95例行乳腺癌根治术患者的临床资料。回顾性收集2022年1月-2023年1月期间本院收治的95例行乳腺癌根治术患者的临床资料。根据麻醉方案分为对照组(全身麻醉,n=47)和观察组(超声引导下肋横突孔阻滞复合全身麻醉,n=48)。分析比较两组的血流动力学、疼痛程度、镇痛效果以及应激反应。结果:两组T1、T2、T3时的心率、平均动脉压均较T0时降低,但观察组的降低幅度均显著小于对照组(P<0.05)。观察组术后6 h、12 h、24 h时的视觉模拟评分法(Visual analogue scale,VAS)评分均显著低于对照组(P<0.05)。观察组术后6 h、12 h、24 h时的Ramsay镇静评分均显著低于对照组(P<0.05)。术后24 h,观察组的去甲肾上腺素、血管紧张素Ⅱ水平的升高幅度均显著低于对照组(P<0.05)。结论:超声引导肋横突孔阻滞复合全身麻醉可稳定乳腺癌根治术患者的血流动力学,强化镇痛和镇静效果,减轻应激反应。Objective:To investigate the effect of ultrasound-guided costotransverse foramina block combined with general anesthesia in patients undergoing radical mastectomy.Methods:The clinical data of 95 patients undergoing radical mastectomy from January 2022 to January 2023 were retrospectively analyzed.The clinical data of 95 patients undergoing radical mastectomy in our hospital from January 2022 to January 2023 were retrospectively collected.According to the anesthesia program,they were divided into control group(general anesthesia,n=47)and observation group(ultrasound-guided costotransverse foramen block combined general anesthesia,n=48).The hemodynamics,pain degree,analgesic effect and stress response of the two groups were analyzed and compared.Results:The heart rate and mean arterial pressure at T1,T2 and T3 were all lower than those at T0,but the decreases in the observation group were significantly smaller than those in the control group(P<0.05).The Visual analogue scale(VAS)scores of the observation group at 6 hours,12 hours and 24 hours were significantly lower than those of the control group(P<0.05).The Ramsay sedation scores of the observation group at 6 hours,12 hours and 24 hours were significantly lower than those of the control group(P<0.05).24 hours after operation,the levels of norepinephrine and angiotensinⅡin observation group were significantly lower than those in control group(P<0.05).Conclusion:Ultrasound-guided costotransverse foramina block combined with general anesthesia can stabilize hemodynamics,enhance analgesia and sedation,and alleviate stress response in patients undergoing radical mastectomy.
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