Asymptomatic pancreatic enlargement without pancreatic enzyme elevation:a rare case of immune checkpoint inhibitor-associated pancreatitis  

作　　者：Yasuki Hori Tatsuya Kawai Aya Naiki-Ito Itaru Naitoh Michihiro Yoshida Akihisa Kato Hiromi Kataoka 

机构地区：[1]Department of Gastroenterology and Metabolism,Nagoya City University Graduate School of Medical Sciences,Nagoya,Japan [2]Department of Radiology,Nagoya City University Midori Municipal Hospital,Nagoya,Japan [3]Department of Experimental Pathology and Tumor Biology,Nagoya City University Graduate School of Medical Sciences,Nagoya,Japan [4]Department of Gastroenterology,Nagoya City University Midori Municipal Hospital,Nagoya,Japan

出　　处：《Gastroenterology Report》2024年第1期827-829,共3页胃肠病学报道(英文)

基　　金：supported by JSPS KAKENHI Grant Number[22K16027];The Hori Sciences and Arts Foundation Grant Number[JOSE205003].

摘　　要：Introduction Immune checkpoint inhibitors(ICIs)have shown clinical efficacy in the treatment of various malignancies[1,2].The grading system for ICI-associated pancreatitis is based on elevated levels of pancreatic enzymes,radiological findings,and/or clinical findings[3].Most cases of ICI-associated pancreatitis exhibit symptoms and/or pancreatic enzyme elevation,but imaging changes are often not dramatic[4].Here,we presented the case of a patient with asymptomatic pancreatic enlargement without the enzyme elevation.She was diagnosed with ICI-associated pancreatitis via endoscopic ultrasound-guided fine-needle biopsy(EUS-FNB)and treated with immunosuppressive therapy.

关 键 词：PANCREATITIS needle clinical 

分 类 号：R576[医药卫生—消化系统]