血糖指标与乳腺癌发病关系的流行病学研究进展  

Progress on Epidemiological Studies for the Relationship Between Plasma Glucose Indicators and Breast Cancer Risk

作　　者：唐丹丹 姜玉[4] 刘湾湾 李卓颖 沈秋明 徐群[5] 项永兵[2,3,5] TANG Dandan;JIANG Yu;LIU Wanwan;LI Zhuoyin;SHEN Qiuming;XU Qun;XIANG Yongbing(School of Public Health,Shanghai Jiao Tong University,Shanghai 200025,China;Department of Epidemiology,Shanghai Cancer Institute,Shanghai 200032,China;State Key Laboratory of Systems Medicine for Cancer,Shanghai Cancer Institute,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200032,China;Shanghai Changning District Center for Disease Control and Prevention,Shanghai 200051,China;Health Management Center,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China)

机构地区：[1]上海交通大学公共卫生学院,上海200025 [2]上海市肿瘤研究所流行病学研究室,上海200032 [3]上海交通大学医学院附属仁济医院上海市肿瘤研究所肿瘤系统医学全国重点实验室,上海200032 [4]上海市长宁区疾病预防控制中心,上海200051 [5]上海交通大学医学院附属仁济医院健康管理中心,上海200127

出　　处：《中国肿瘤》2025年第1期67-72,共6页China Cancer

基　　金：国家重点研发计划(2021YFC2500404,2021YFC2500405);长宁区医学硕博士创新人才基地“多维度糖尿病管理”(RCJD2021S06)。

摘　　要：高血糖是糖尿病的主要生物学特征之一。糖负荷后2小时血糖(2-hour postload glucose,2h PG)、空腹血糖(fasting plasma glucose,FPG)和糖化血红蛋白(glycated hemoglobin,HbA1c)是临床上常用于检测血糖水平的3项重要指标,但这些指标与乳腺癌发病的关联尚不明确。全文对基于以上3项指标探讨血糖水平与乳腺癌关系的研究作一综述,以期为乳腺癌的一级预防中血糖管理策略的制定提供参考依据。Hyperglycemia is a primary biological characteristic of diabetes.It is well known that three key indicators are commonly used in clinical practice to measure plasma glucose levels,such as 2-hour postload glucose(2hPG),fasting plasma glucose(FPG),and glycated hemoglobin(HbA1c).However,the association between these indicators and breast cancer incidence remains unclear.This paper systematically reviews the relationship between plasma glucose levels and breast cancer based on the above three indicators,to provide a reference for the formulation of effective plasma glucose management strategies for the primary prevention of breast cancer.

关 键 词：乳腺癌 糖负荷后2小时血糖 空腹血糖 糖化血红蛋白 流行病学 

分 类 号：R737.7[医药卫生—肿瘤]