Safety and effectiveness of balloon catheter-assiste d ultrasound-guide d percutaneous microwave ablation in difficult-site liver cancer  

作　　者：Qi-Yu Zhao Teng Guo Jing-Jing Hu Li-Ting Xie Wei-Lu Chai Guo Tian Tian-An Jiang 

机构地区：[1]Department of Ultrasound Medicine,the First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China [2]Department of Hepatobiliary and Pancreatic Surgery,the First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China [3]Department of Ultrasound Medicine,the First Affiliated Hospital,Zhejiang University School of Medicine,Liangzhu Branch,Hangzhou 310003,China [4]Department of Ultrasound Medicine,Ningbo No.2 Hospital,Ningbo 315010,China

出　　处：《Hepatobiliary & Pancreatic Diseases International》2025年第1期84-91,共8页国际肝胆胰疾病杂志(英文版)

基　　金：supported by a grant from the National Natural Science Foundation of China (82171937)。

摘　　要：Background:Balloon catheter isolation is a promising auxiliary method for thermal ablation treatment of liver cancer. We aimed to explore the safety and effectiveness of balloon catheter isolation-assisted ultrasound-guided percutaneous microwave ablation (MWA) in treating liver cancer in difficult anatomical locations.Methods:Data of 132 patients with 145 difficult-site liver cancer treated with ultrasound-guided percutaneous MWA were retrospectively analyzed. Participants were classified into the isolation (n=40)and non-isolation (n=92) groups based on whether the patients were treated using a balloon catheter prior to ablation. The major complication rates, local tumor residuals (LTR), and tumor follow-up for local tumor progression (LTP) at 6 and 12 months post-ablation were compared between the two groups.Results:The rates of major postoperative complications did not significantly differ between the isolation and non-isolation groups (2.5%vs. 4.3%, P=0.609). The postoperative LTR rates were significantly different between the isolation and non-isolation groups (4.8%vs. 17.5%, P=0.032). Balloon catheter isolation [odds ratio (OR)=0.225, 95%confidence interval (CI):0.085–0.595, P=0.009] and tumor diameter(OR=2.808, 95%CI:1.186–6.647, P=0.019) were identified as independent factors influencing LTR rate.The cumulative LTP rates at 6 and 12 months after ablation showed no significant differences between the isolation and non-isolation groups (2.6%vs. 7.9%, P=0.661;4.9%vs. 9.8%, P=0.676, respectively).Cox proportional hazards regression analysis showed that tumor diameter was an independent risk factor for cumulative LTP rate (OR=3.445, 95%CI:1.406–8.437, P=0.017).Conclusions:Balloon catheter isolation-assisted MWA was safe and effective in the treatment of difficultsite liver cancer. Additionally, tumor diameter significantly influenced LTR and LTP rates after ablation.

关 键 词：Liver cancer Microwave ablation Balloon catheter isolation 

分 类 号：R73[医药卫生—肿瘤]