非小细胞肺癌患者术后病理分期升级的影响因素分析  

To Analyze the Influencing Factors of Postoperative Pathological Staging Upgrade in Patients with Non-small Cell Lung Cancer

作　　者：米丽班古丽·西克然木 Milibanguli Xikeranmu(Department of Pathology,The Sixth Affiliated Hospital of Xinjiang Medical University,Wulumuqi Xinjiang 830092,China)

机构地区：[1]新疆医科大学第六附属医院病理科,新疆乌鲁木齐830092

出　　处：《生命科学仪器》2024年第6期73-75,共3页Life Science Instruments

摘　　要：目的分析非小细胞肺癌患者术后病理分期升级的影响因素。方法回顾性分析2022年5月至2023年5月期间新疆医科大学第六附属医院呼吸科收治的非小细胞肺癌患者124例。收集患者一般临床资料,按照术后是否发生病理分期升级,分为非升级组(n=72)和升级组(n=52)。采用多元线性回归方法,分析影响术后病理分期升级的危险因素。结果单因素分析显示,升级组和非升级组年龄、发现方式、肿瘤直径、术后辅助化疗和术后危险因素评分比较(P<0.05)。多因素分析显示,年龄≥60岁、未术后辅助化疗和术后危险因素评分≥2分是非小细胞肺癌患者术后病理分期升级的危险因素(P<0.05)。非升级组6个月、12个月存活率均高于升级组(P<0.05)。结论非小细胞患者术后病理升级的影响因素多,老年患者、未术后辅助化疗和术后危险因素评分≥2分的患者术后发生病理升级的风险较高,需引起临床高度重视,并及早采取相应的干预措施。Objective:To analyze the influencing factors of postoperative pathological staging and upgrading in patients with non-small cell lung cancer Methods:From May 2022 to May 2023,124 cases of non-small cell lung cancer were analyzed retrospectively.The general clinical data of patients were collected,and they were divided into non-escalation group(n=72)and escalation group(n=52)according to whether pathological staging occurred after operation.Multiple linear regression method was used to analyze the risk factors affecting the postoperative pathological staging and upgrading.Results:Univariate analysis showed that the age、the way of finding、the diameter of tumor、postoperative adjuvant chemotherapy and postoperative risk factors were compared between the upgraded group and the non-upgraded group(P<0.05).Multivariate analysis showed that age≥60 years、no postoperative adjuvant chemotherapy and postoperative risk factor score≥2 were the risk factors for postoperative pathological staging and upgrading of patients with non-small cell lung cancer(P<0.05).The 6-month and 12-month survival rates of the non-upgraded group were higher than those of the upgraded group(P<0.05).Conclusion:There are many factors influencing postoperative pathological escalation in patients with non-small cell disease.Elderly patients,patients without postoperative adjuvant chemotherapy and patients with postoperative risk factors score≥2 are at higher risk of postoperative pathological escalation,which needs to be paid great attention to in clinic and corresponding intervention measures should be taken as soon as possible.

关 键 词：非小细胞肺癌 术后辅助化疗 病理分期升级 

分 类 号：R734.2[医药卫生—肿瘤]