伴中央颞区棘波的自限性癫痫患儿发生睡眠中癫痫性电持续状态的相关因素及脑电图特点  

Analysis of Related Factors And EEG Characteristics of Epileptic Electrical Status During Sleep in Children with Epilepsy with Central Temporal Spasm

作　　者：许沈洁[1] Xu Shenjie(Department of Neurology,the First People's Hospital of Changzhou(EEG),Changzhou Jiangsu 213000,China)

机构地区：[1]常州市第一人民医院神经内科(脑电图),江苏常州213000

出　　处：《生命科学仪器》2024年第6期17-19,共3页Life Science Instruments

摘　　要：目的分析伴中央颞区棘波的自限性癫痫(BECTS)患儿发生睡眠中癫痫性电持续状态(ESES)的相关因素,探讨其脑电图特点。方法纳入常州市第一人民医院神经内科2022年9月至2024年3月期间收治的BECTS患儿80例,进行发作期脑电图检查,根据病程中是否出现ESES分为伴有ESES组(n=37例)和不伴有ESES组(n=43例),进行单因素及多因素分析。结果伴有ESES组治疗后癫痫复发、发作次数>2次/年、用药种类、双侧放电、放电部位为高位中央区占比均高于不伴有ESES组,P<0.05。Logistic分析显示,治疗后癫痫复发、发作次数>2次/年、用药种类、双侧放电为BECTS患儿出现ESES的高危因素(P<0.05)。结论BECTS患儿发生ESES具有一些脑电图特点,此外,其高危因素与治疗后癫痫复发、发作次数、用药种类等密切相关,临床需要针对上述高危因素,采用针对性干预措施,以减少癫痫发作。Objective:To analyze the related factors of epileptic electrical status during sleep(ESES)in children with self-limited epilepsy(BECTS)with spikes in the central temporal region,and to explore the EEG characteristics.Methods:Eighty children with BECTS who were admitted to the Department of Neurology,Changzhou First People's Hospital from September 2022 to March 2024 were examined by electroencephalography(EEG)during the attack period.According to whether there was ESES in the course of the disease,they were divided into two groups:group with ESES(n=37)and group without ESES(n=43),and univariate and multivariate analysis were conducted.Results:In the group with ESES、the recurrence of epilepsy、the number of seizures>2 times/year、the types of drugs、bilateral discharge and the high central area of discharge were higher than those in the group without ESES,P<0.05.Logistic analysis showed that the recurrence of epilepsy after treatment,the number of seizures>2 times/year,the types of drugs and bilateral discharge were the high risk factors for ESES in children with BECTS(P<0.05).Conclusion:ESES in children with BECTS has some EEG characteristics.In addition,its high-risk factors are closely related to the recurrence of epilepsy after treatment、the number of seizures、the types of drugs,etc.Clinically,targeted intervention measures should be taken to reduce seizures.

关 键 词：伴中央颞区棘波的癫痫 睡眠中癫痫性电持续状态 脑电图 

分 类 号：R742.1[医药卫生—神经病学与精神病学]