2013-2022年深圳市南山区早发型消化道癌症发病及趋势分析  

Incidence and trend of early-onset gastrointestinal cancer in Nanshan District,Shenzhen,from 2013 to 2022

作　　者：罗绍锋 刘海风 彭晓琳 赵丹 欧阳斌发 李改瑞 何志飞 邹泉 钟旋 LUO Shaofeng;LIU Haifeng;PENG Xiaolin;ZHAO Dan;OUYANG Binfa;LI Gairui;He Zhifei;ZOU Quan;ZHONG Xuan(Department of Tumor Injury and Nutrition,Chronic Disease Prevention and Treatment Hospital,Shenzhen 518000,China)

机构地区：[1]广东省深圳市南山区慢性病防治院肿瘤伤害与营养科,518000 [2]广东医科大学公共卫生学院

出　　处：《中国煤炭工业医学杂志》2024年第5期540-546,共7页Chinese Journal of Coal Industry Medicine

基　　金：深圳市科技创新委员会面上项目(编号:JCYJ20220531091804010);深圳市南山区科技创新局资助项目(编号:NS2024002);南山区医学重点学科建设项目(慢性非传染性疾病)

摘　　要：目的 了解深圳市南山区2013-2022年早发型消化道癌症的发病率及其变化趋势,为针对性开展防控措施提供依据。方法 基于深圳市慢性病防治管理系统所登记的南山区2013-2022年20~49岁常住人口中诊断为消化道癌症的全部首发病例数据。计算早发型消化道癌症的粗发病率、年龄别发病率、中标率、世标率,并通过年度发病变化百分比(APC)了解发病状况。结果 2013-2022年南山区共报告早发型消化道癌症新发病例1 328例,粗发病率为12.73/10万,中标率为15.05/10万,世标率为13.90/10万。男女发病比例为1.86:1。Joinpoint回归分析APC和AAPC结果均显示,合计中标率为-3.4%,男性中标率为-3.1%,女性中标率为-3.7%;合计世标率APC为-3.4%,男性世标率为-3.1%,女性世标率为-3.7%。2013-2022年早发型消化道癌症的发病趋势未发生显著变化(P>0.05),但其中的胃癌发病呈现出明显的下降趋势(P=0.014),而结直肠癌和肝癌的发病趋势稳定(P>0.05)。结论 尽管南山区早发型消化道癌症的发病趋势稳定,在现有区域性癌症综合防控体系下,仍需加强对早发型结直肠癌和早发型肝癌的早筛工作以降低消化道癌症的发病率,提高中青年人群的生命质量和健康水平。Objective To understand the incidence and change trend of early-onset gastrointestinal cancer from 2013 to 2022,to provide a basis for targeted prevention and control measures.Methods Based on the data of all primary cases diagnosed with gastrointestinal cancer in Nanshan District from 2013 to 2022 registered in Shenzhen Chronic Disease Prevention and Management System.The Crude incidence,age-specific incidence,age-standardized rate by Chinese standard population in 2010 and Segi’s world population in 2000(ASR China and ASR world)of early-onset gastrointestinal cancer were calculated and the incidence status was understood by the percentage change of annual incidence rate(APC).Results From 2013 to 2022,a total of 1328 new cases of early-onset gastrointestinal cancer were reported in Nanshan District,with a crude incidence rate of 12.73/105,with ASR China of 15.05/105,and ASR World of 13.90/105.The ratio of male to female incidence was 1.86:1.The results of Joinpoint regression analysis of APC and AAPC showed that the ASR China was-3.4%,the male ASR China was-3.1%,and the female ASR China was-3.7%;the ASR world was-3.4%,the male ASR world was-3.1%,and the female ASR world was-3.7%.The results of Joinpoint regression analysis showed that the incidence trend of early-onset gastrointestinal cancer did not change significantly from 2013 to 2022(P>0.05).In early-onset gastrointestinal cancers,the incidence of gastric cancer showed a significant downward trend(P=0.014),while the incidence trend of colorectal cancer and liver cancer was stable(P>0.05).Conclusion Although the incidence trend of early-onset digestive tract cancer in Nanshan District was stable,under the existing regional comprehensive cancer prevention and control system,early screening of early-onset colorectal cancer was still needed to reduce the incidence of digestive tract cancer and then improve the quality of life and health level of young and middle-aged people.

关 键 词：早发型消化道癌症 发病率 变化趋势 

分 类 号：R735[医药卫生—肿瘤]