响应面法优化豆渣制备粗微晶纤维素  

Optimization of preparing crude microcrystalline cellulose from okara by response surface methodology

作　　者：徐露 孙崇庆 许德华 严正娟 李雪 钟本和 王辛龙 XU Lu;SUN Chongqing;XU Dehua;YAN Zhengjuan;LI Xue;ZHONG Benhe;WANG Xinlong(Ministry of Education Research Center for Comprehensive Utilization and Clean Processing Engineering of Phosphorus Resources,School of Chemical Engineering,Sichuan University,Chengdu 610065,China)

机构地区：[1]四川大学化学工程学院,教育部磷资源综合利用与清洁加工工程研究中心,成都610065

出　　处：《化学工业与工程》2025年第1期1-8,共8页Chemical Industry and Engineering

基　　金：原位增值水溶肥及中微量元素肥料创制与产业化(2023YFD1700204);陕煤-秦岭基础科学研究五年行动计划协同创新合作协议(22H1098);四川大学磷资源高效利用工科特色团队(2020SCUNG113)

摘　　要：以豆渣为原料,利用氢氧化钾与湿法磷酸联合处理制备粗微晶纤维素(Crude Microcrystalline Cellulose, CMCC)。以结晶指数为响应值利用单因素实验、Plackett-Burman实验、响应面优化实验对工艺条件进行优化。结果表明:碱解温度、酸解温度、酸解时间对CMCC的结晶指数影响较为显著,最适宜工艺条件为:碱解温度90℃、碱解时间60 min、氢氧化钾溶液浓度4%(质量分数)、湿法磷酸质量分数35%(P_(2)O_(5)的质量分数,下同)、酸解时间60 min、酸解温度95℃。验证试验表明最适宜条件下所得CMCC产品结晶指数为42.89%,仅比预测值低0.12%,表明利用响应面优化法得到的优化结果合理可行。In this study,crude microcrystalline cellulose(CMCC)was prepared from soybean residue(okara)through combined treatment of potassium hydroxide and wet-process phosphoric acid.The crystallinity index was chosen as the response value and single factor experiments,Plackett-Burman experiments,and response surface methodology were used to optimize process conditions.The results suggested that alkali treatment temperature,acid treatment temperature,and acid treatment time had a significant impact on crystallinity index of CMCC and the optimal process conditions were identified as alkali treatment temperature 90℃,alkali treatment time 60 min,potassium hydroxide solution concentration 4%,wet-process phosphoric acid concentration 35%(P_(2)O_(5)),acid treatment time 60 min,and acid treatment temperature 95℃.The confirmatory experiment indicated the crystallinity index of CMCC was 42.89%under optimal conditions,which was only 0.12 percentage points lower than the predicted value,indicating that the optimization results obtained by the response surface optimization method are reasonable and feasible.

关 键 词：豆渣 粗微晶纤维素 结晶指数 Plackett-Burman实验 响应面优化实验 

分 类 号：TQ352.79[化学工程]