Forty years of practice against gastric cancer in Linqu County, a high-risk area of gastric cancer in China  

作　　者：Kai‐Feng Pan Wen‐Qing Li Wei‐Cheng You 

机构地区：[1]State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers,Beijing Key Laboratory of Carcinogenesis and Translational Research,Department of Cancer Epidemiology,Peking University Cancer Hospital&Institute,Beijing,China [2]Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Department of Cancer Epidemiology,Peking University Cancer Hospital&Institute,Beijing,China

出　　处：《Malignancy Spectrum》2024年第3期141-146,共6页肿瘤学全景(英文)

基　　金：government of Linqu County for supporting this work;supported by the Key International S&T Cooperation Project of the Ministry of Science and Technology of China (2010DFB30310);the National Basic Research Program of China (973 program: 2004CB518702 and 2010CB529303);the Intramural Research Program of the National Institutes of Health, National Cancer Institute;in part by the National Cancer Institute Contracts NO2-CP-71103 and NO2CP-21169;Peking University Cancer Hospital & Institute, China, German Federal Ministry of Education and Research (BMBF) (German Research Presence in Asia: 01DO17022, CHN 11/021);DZIF German Centre for Infection Research, München, Germany

摘　　要：Gastric cancer(GC)is a global public health burden,with nearly one million new cases diagnosed each year worldwide.To investigate the risk factors and the prevention strategies for GC,in the past 40 years,a series of epidemiological studies have been carried out in Linqu County,Shandong Province,a high-risk area of GC in China.Here,we briefly review the major efforts of 40-year practices against GC in Linqu County,particularly highlighting a case-control study to identify GC risk factors,a cohort study to determine the associations between the risk factors and the progression of gastric lesions,and an intervention trial to prevent GC development.

关 键 词：gastric cancer precancerous gastric lesions Helicobacter pylori risk factor PREVENTION 

分 类 号：R735.2[医药卫生—肿瘤]