血管内介入栓塞术在颅内动脉瘤治疗中的临床效果观察  

Clinical Observation of Endovascular Interventional Embolization in the Treatment of Intracranial Aneurysms

作　　者：蔡卓言 Cai Zhuoyan(Hunan Provincial People's Hospital(the first affiliated hospital of the Hunan Normal University),Changsha Hunan 410005,China)

机构地区：[1]湖南省人民医院(湖南师范大学附属第一医院),湖南长沙410005

出　　处：《生命科学仪器》2024年第5期126-128,共3页Life Science Instruments

摘　　要：目的 探讨分析血管内介入栓塞术在颅内动脉瘤(IA)治疗中的临床疗效。方法 选择2023年3月至2024年3月湖南省人民医院(湖南师范大学附属第一医院)收治的IA患者100例,采用随机数表法分为观察组和对照组,每组50例。对照组给予动脉瘤夹闭手术治疗,观察组给予血管内介入栓塞术治疗。对比两组临床效果。结果 经过治疗,观察组栓塞程度较对照组更轻,P<0.05。术后14 d,观察组血管内皮指标NO、ET-1及VEGF均优于对照组,NIHSS、Rankin及SF-36评分均优于对照组,P<0.05。结论 血管内介入栓塞术治疗IA患者可有效改善栓塞程度,优化血管内皮指标、神经功能及患者生活质量。Objective:To explore and analyze the clinical effect of endovascular interventional embolization in the treatment of intracranial aneurysm(IA).Methods:100 patients with IA admitted to Hunan Provincial People's Hospital(the First Affiliated Hospital of Hunan Normal University)from March 2023 to March 2024 were randomly divided into observation group and control group,with 50 patients in each group.The control group was treated with aneurysm clipping operation,while the observation group was treated with intravascular interventional embolization.The clinical effects of the two groups were compared.Results:After treatment,the degree of embolism in the observation group was lighter than that in the control group,P<0.05.On 14th day after operation,the vascular endothelial indexes NO、ET-1 and VEGF in the observation group were better than those in the control group,and the scores of NIHSS、Rankin and SF-36 were better than those in the control group,P<0.05.Conclusion:Intravascular interventional embolization can effectively improve the degree of embolization,optimize vascular endothelial index、neurological function and quality of life of patients with IA.

关 键 词：血管内介入 颅内动脉瘤 血管内皮指标 栓塞程度 

分 类 号：R739.41[医药卫生—肿瘤]