Analysis on Chemical Components of Meconopsis integrifolia(Maxim.)Franch Total Flavonoids by UPLC-Q-Exactive Orbitrap MS  

作　　者：Yifan TIAN Yuanlin KONG Limin LI Zhengming YANG Chaoqin REN Yongcang ZHANG Yuan LIU Yanfei HUANG 

机构地区：[1]College of Pharmacy,Qinghai-Tibetan Plateau Ethnic Medicinal Resources Protection and Utilization Key Laboratory of National Ethnic Affairs Commission of the People s Republic of China,Southwest Minzu University,Chengdu 610225,China [2]Sichuan Academy of Chinese Medicine Sciences,Chengdu 610042,China [3]College of Resources and Environment,Aba Teachers College,Wenchuan 623002,China [4]Medical College,Tibet University,Lhasa 850000,China

出　　处：《Medicinal Plant》2025年第1期1-10,共10页药用植物(英文)

基　　金：Supported by Natural Science Foundation of Sichuan Province(2023NS-FSC0610);the Special Fund of Natural Science for the Central Universities of Southwest Minzu University(ZYN2023071).

摘　　要：[Objectives]To analyze the chemical components of Meconopsis integrifolia(Maxim.)Franch total flavonoids(MITF).[Methods]The chemical components of MITF were identified by UPLC-Q-Exactive Orbitrap MS.The column was performed using ACQUITY UPLC HSS T3(100 mm×2.1 mm,1.8μm)with 0.1%formic acid water(A)-acetonitrile(B)with gradient elution at 30℃,injection volume of 2μL,and flow rate of 0.3 mL/min.Electrospray ion source adopted positive and negative ion detection mode with scanning range m/z 100-1000.[Results]A total of 93 compounds were identified from MITF,including 57 flavonoids,25 phenolic acids,9 alkaloids and 2 others.Among them,dimethoxytaxifolin was identified as a possible new compound by SciFinder search,and 67 compounds were first identified in M.integrifolia.[Conclusions]This study provides a scientific foundation for clarifying the material basis of the efficacy of M.integrifolia and improving the quality standards.

关 键 词：Meconopsis integrifolia(Maxim.)Franch UPLC-Q-Exactive Orbitrap MS Total flavonoids ALKALOIDS Phenolic acids 

分 类 号：R286[医药卫生—中药学]