原发舌前腺恶性肿瘤的临床特征及治疗策略  

Clinical Features and Therapeutic Strategies in Primary Malignant Tumors of Anterior Lingual Gland

作　　者：李馥焰 王睿 许慧霞 孙国文[1] LI Fuyan;WANG Rui;XU Huixia;SUN Guowen(Nanjing Stomatological Hospital,Affiliated Hospital of Medical School,Institute of Stomatology,Nanjing University,Nanjing 210008,China)

机构地区：[1]南京大学医学院附属口腔医院,南京市口腔医院,南京大学口腔医学研究所,江苏南京210008

出　　处：《口腔医学研究》2025年第2期118-121,共4页Journal of Oral Science Research

基　　金：南京市卫生科技发展专项资金项目(编号:YKK22183)。

摘　　要：目的:回顾性分析9例舌前腺肿瘤患者临床资料,深入探讨其临床特点、治疗策略及预后情况,以期为临床治疗提供有价值的参考。方法:2010年11月~2023年11月,南京大学医学院附属口腔医院(南京市口腔医院)口腔颌面外科收治舌恶性肿瘤患者1619例,所有患者均进行了手术治疗,其中的9例为舌前腺恶性肿瘤,并对此类病变进行回顾性分析。结果:9例患者中,腺样囊性癌4例,黏液表皮样癌4例,透明细胞癌1例。组织缺损较小者,直接拉拢缝合;组织缺损较大者,进行皮瓣修复:4例前臂皮瓣,1例上臂外侧肌皮瓣,1例颏下岛状皮瓣。所有患者均预后良好。结论:舌前腺肿瘤虽然发病率较低,但一旦发病,其恶性程度往往较高,以腺样囊性癌、黏液表皮样癌和透明细胞癌为主要病理类型;临床表现为舌尖腹部界限尚清的肿块,质地中等偏硬,活动度较差。手术切除是治疗舌前腺肿瘤的首选方法,术后辅助治疗的决策则根据肿瘤的具体性质和手术的具体情况来定。Objective:To retrospectively analyze 9 patients with anterior lingual gland tumors,and discuss their clinical characteristics,treatment strategies,and prognosis.Methods:Between November 2010 and November 2023,1619 patients with“tongue malignancy”were admitted to the Department of Oral and Maxillofacial Surgery of the Affiliated Stomatological Hospital of the School of Medicine of Nanjing University(Nanjing Stomatological Hospital).All of them underwent surgical treatments,and 9 of them had malignant tumors of the anterior lingual glands,which were retrospectively analyzed.A retrospective analysis of these lesions was performed.Results:Among 9 patients,4 cases were adenoid cystic carcinoma,4 cases were mucoepidermoid carcinoma,and 1 case was clear cell carcinoma.Those with small tissue defects were directly pulled together and sutured,and those with large tissue defects were repaired with flaps:4 cases of forearm flap,1 case of lateral muscle flap of the upper arm,and 1 case of under-chin island flap.The prognosis of all patients was good.Conclusion:Although the incidence of anterior lingual glandtumors is relatively low,once developed,its malignant degree is often high,with adenoid cystic carcinoma,mucoepidermoid carcinoma,and clear cell carcinoma as the main types.The clinical manifestation is a well-demarcated mass in the abdomen of the tip of the tongue,with moderately hard texture and poor mobility.Surgical resection is the treatment of choice for anterior lingual gland tumors,and the decision of postoperative adjuvant therapy is based on the specific nature of the tumor and the specifics of the surgery.

关 键 词：舌前腺 腺样囊性癌 黏液表皮样癌 透明细胞癌 

分 类 号：R73[医药卫生—肿瘤]