拔牙列点保存治疗种植牙修复患者的疗效及对疼痛程度、氧化应激指标的影响  

Curative effect of tooth extraction site preservation in the treatment of patients with implant restoration and its influence on pain degree and oxidative stress index

作　　者：魏娜 郑冬冬 付欣 刘硕[1] WEI Na;ZHENG Dong-dong;FU Xin(Department of Stomatology,Handan First Hospital,Handan Hebei 056002,China)

机构地区：[1]邯郸市第一医院口腔科,河北邯郸056002

出　　处：《临床和实验医学杂志》2025年第1期103-107,共5页Journal of Clinical and Experimental Medicine

基　　金：河北省卫生健康委科研基金项目(编号:20200431)。

摘　　要：目的探究拔牙列点保存治疗种植牙修复患者的疗效及对疼痛程度、氧化应激指标的影响。方法回顾性选取2022年6月至2023年6月邯郸市第一医院口腔科收治的110例种植牙修复患者(158颗)作为研究对象,按照治疗方法不同分为对照组与观察组,每组各55例。对照组患者采取常规植牙操作,观察组采取预保留拔牙列点技术种植牙修复,均随访6个月。比较两组患者的种植成功率,治疗前、治疗6个月后的牙槽骨吸收量、美学效果[粉色美学评分(PES)]、牙槽骨变化情况(牙槽骨宽度、高度和密度)、疼痛程度[视觉模拟评分法(VAS)评分]、氧化应激指标[超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、血管紧张素(Ang)Ⅱ],并记录两组患者不良反应发生情况。结果两组种植成功率比较,差异无统计学意义(P>0.05);治疗6个月后,两组牙槽骨吸收量均较治疗前降低,PES评分均较治疗前升高,且观察组的牙槽骨吸收量为(0.85±0.48)mm,明显低于对照组[(1.76±0.35)mm],PES评分为(12.99±1.72)分,明显高于对照组[(12.06±1.21)分],差异均有统计学意义(P<0.05)。治疗6个月后,两组的牙槽骨宽度、高度及密度均较治疗前降低,但观察组的牙槽骨宽度、高度及密度分别为(7.86±1.05)mm、(11.02±1.31)mm、(431.24±47.92)HU,均显著高于对照组[(7.15±0.98)mm、(10.23±1.25)mm、(402.35±48.76)HU],差异均有统计学意义(P<0.05)。治疗6个月后,两组VAS评分均较治疗前降低,且观察组VAS评分为(2.39±0.23)分,明显低于对照组[(4.23±0.33)分],差异均有统计学意义(P<0.05)。治疗6个月后,两组SOD、AngⅡ含量均较治疗前升高,GSH-Px含量明显降低,且观察组的SOD、AngⅡ含量分别为(52.36±4.38)U/mL、(131.16±9.15)mmol/L,均明显低于对照组[(77.19±4.69)U/mL、(198.43±9.01)mmol/L],GSH-Px含量为(54.15±5.16)U/L,明显高于对照组[(34.52±5.06)U/L],差异均有统计学意义(P<0.05)。观察组患者的总并�Objective To explore the effect of tooth extraction site preservation in the treatment of patients with implant restoration and its influence on pain degree and oxidative stress index.Methods A total of 110 patients(158 teeth)with dental implant repair admitted to the Department of Stomatology,Handan First Hospital from June 2022 to June 2023 were retrospectively selected as the research objects.According to the different treatment methods,they were divided into the control group and the observation group,with 55 cases in each group.The control group was treated with conventional dental implant operation,and the observation group was treated with pre preserved extraction site technology.All patients were followed up for 6 months.The implant success rate,alveolar bone absorption,aesthetic effect[pink esthetic score(PES)],alveolar bone changes(alveolar bone width,height and density),pain degree[visual analogue scale(VAS)score],oxidative stress index[superoxide dismutase(SOD),glutathione peroxidase(GSH-Px),angiotensin(Ang)Ⅱ]before treatment and 6 months after treatment were compared between the two groups,and the incidence of adverse reactions in the two groups were recorded.Results There was no statistically significant difference in the success rate of implantation between the two groups(P>0.05).After 6 months of treatment,the alveolar bone absorption of the two groups was lower than that before treatment,and the PES score was higher than that before treatment.The alveolar bone absorption of the observation group was(0.85±0.48)mm,which was significantly lower than that of the control group[(1.76±0.35)mm],the PES score was(12.99±1.72)points,which was significantly higher than that of the control group[(12.06±1.21)points],and the differences were statistically significant(P<0.05).After 6 months of treatment,the width,height and density of alveolar bone in the two groups were lower than those before treatment,but the width,height and density of alveolar bone in the observation group were(7.86±1.05)mm,(11.02±1

关 键 词：拔牙列点保留 种植牙 骨缺失 美观程度 口腔种植术 

分 类 号：R783.6[医药卫生—口腔医学]