药源性葡萄膜炎病因的研究进展  

RESEARCH PROGRESS ON ETIOLOGY OF DRUG-INDUCED UVEITIS

作　　者：刘历东[1] 杨大勇[1] LIU Lidong;YANG Dayong(Department of Ophthalmology,The Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010050,China)

机构地区：[1]内蒙古医科大学附属医院眼科,内蒙古呼和浩特010050

出　　处：《内蒙古医科大学学报》2024年第5期552-557,共6页Journal of Inner Mongolia Medical University

基　　金：内蒙古医科大学附属医院青年骨干项目(2022NYFYFG008)。

摘　　要：由于使用各种药物出现的葡萄膜炎称为药源性葡萄膜炎(DIU),在非感染性葡萄膜炎中,药源性是致病因素之一,虽然患病率低,但随着近年来各种新型药物剂型和给药方式的应用,临床可见多种药物所致葡萄膜炎。目前认为全身、局部或玻璃体内各种用药途径、疫苗注射,都可能是药源性葡萄膜炎的致病因素,眼部炎症可表现为前、中、后或全葡萄膜炎,表层巩膜炎、巩膜炎也有报道。通过多次停用该药物或同时使用皮质类固醇可以治疗葡萄膜炎,从而确定该药物是葡萄膜炎的可能致病因素。Uveitis maybe induced by the use of various medications known as drug induced uveitis(DIU),though rare it is an important cause of uveitis which one needs to be aware of.The drugs may be administered through any route including systemic,topical,and intravitreal.Ocular inflammation can be in the form of anterior,intermediate,posterior or pan uveitis,and rarely may present as episcleritis and scleritis.Identification of drug as the offending agent of uveitis is important as many a times stopping the drug may help recover the uveitis or the concomitant use of corticosteroids.

关 键 词：药源性葡萄膜炎 玻璃体内药物葡萄膜炎 全身药物葡萄膜炎 局部葡萄膜炎 疫苗葡萄膜炎 

分 类 号：R773[医药卫生—眼科]