脂溢性皮炎的发病机制及治疗研究进展  

Pathogenesis and treatment of seborrheic dermatitis

作　　者：王迪 张瑞珺 康玉英 Wang Di;Zhang Ruijun;Kang Yuying(Department of Dermatovenereology,Third Hospital of Shanxi Medical University,Shanxi Bethune Hospital,Shanxi Academy of Medical Sciences,Tongji Shanxi Hospital,Taiyuan 030032,China;Department of Dermatovenereology,Shanxi Bethune Hospital,Shanxi Academy of Medical Sciences,Third Hospital of Shanxi Medical University,Tongji Shanxi Hospital,Taiyuan 030032,China;Department of Dermatology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)

机构地区：[1]山西医科大学第三医院,山西白求恩医院(山西医学科学院),同济山西医院皮肤性病科,太原030032 [2]山西白求恩医院(山西医学科学院),山西医科大学第三医院,同济山西医院皮肤性病科,太原030032 [3]华中科技大学同济医学院附属同济医院皮肤科,武汉430030

出　　处：《中华皮肤科杂志》2025年第1期89-92,共4页Chinese Journal of Dermatology

基　　金：山西省应用基础研究计划(201801D121292);山西省基础研究计划(202303021221196)。

摘　　要：脂溢性皮炎是一种慢性、复发性、炎症性皮肤病,其病因与皮肤微生态失调、脂质代谢异常、皮肤屏障功能受损、免疫反应异常以及遗传因素密切相关。近年来许多新的治疗方法如外用磷酸二酯酶4抑制剂、Janus激酶抑制剂、物理治疗和化学剥脱术等为脂溢性皮炎的治疗提供了更多选择。本文综述了脂溢性皮炎在发病机制和治疗方面的最新研究进展。Seborrheic dermatitis is a chronic,recurrent,and inflammatory skin disease.Its etiology is intricately related to skin microecological imbalance,dysregulated lipid metabolism,impaired skin barrier function,abnormal immune responses,and genetic predispositions.In recent years,several novel therapeutic approaches have emerged,such as topical phosphodiesterase 4 inhibitors,Janus kinase inhibitors,physical interventions,and chemical peeling,providing more options for the treatment of seborrheic dermatitis.This review summarizes the latest research progress in the pathogenesis and treatment of seborrheic dermatitis.

关 键 词：皮炎 脂溢性 治疗学 发病机制 皮肤微生态 

分 类 号：R73[医药卫生—肿瘤]