Correlation of PM_(2.5)pollution and daily mortality rate of cardiovascular and cerebrovascular diseases in Northeast China through PM_(2.5)sources analysis  

作　　者：Qianqi Hong Yang Zhao Jing Wang Hongyan Sun Lanxin Deng Jingjing Cao Cheng Wang 

机构地区：[1]Department of Environmental Hygiene,School of Public Health,Harbin Medical University,Harbin 150081,China [2]Harbin Center for Disease Control and Prevention,Harbin 150056,China

出　　处：《Frigid Zone Medicine》2024年第4期193-201,共9页寒地医学(英文)

基　　金：supported by the National Natural Science Foundation of China(No.82273613);supported by the Research project of Health Commission of Heilongjiang Province(No.20231212010393).

摘　　要：Objective:This study aims to evaluate the relationship between PM_(2.5)concentration and daily mortality rate from cardiovascular and cerebrovascular diseases(CCVD)in cold regions of northern China,as well as to identify the primary sources of PM_(2.5).Methods:A time series analysis model was used to calculate the exposure-response relationship between PM_(2.5)and CCVD mortality in Harbin.Positive matrix factorization(PMF)was employed to analyze the sources of PM_(2.5).Results:After adjusting for multiple pollutant combinations,the maximum excess risk of cardio-cerebrovascular death on the day of PM_(2.5)exposure was 0.42%(95%CI:0.15%-0.70%).Stratification by gender and age revealed that the elderly individuals and men were particularly susceptible to PM_(2.5)exposure.The source analysis identified seven major pollution sources contributing to PM_(2.5)in Harbin.Conclusion:Our findings strengthen the evidence that PM_(2.5)is an independent risk factor for daily CCVD mortality,identify vulnerable populations that require special attention,and pinpoint the primary sources of PM_(2.5)in Harbin.These findings provide reference points for effectively reducing the health risks associated with PM_(2.5)exposure.

关 键 词：PM_(2.5) cardio-cerebrovascular diseases daily mortality time series PMF 

分 类 号：R73[医药卫生—肿瘤]