乳腺癌术后化疗患者采用加味八珍汤辅助治疗的效果及对骨髓抑制的影响  

Effect of Adjuvant Therapy of Modified Bazhen Decoction on Postoperative Chemotherapy of Breast Cancer Patients and Its Influence on Myelosuppression

作　　者：谢邦翔 XIE Bangxiang(The 2nd Department of Internal Medicine,Jian’ou Hospital of Integrated Traditional Chinese and Western Medicine,Nanping 353100,Fujian Province,China)

机构地区：[1]建瓯市中西医结合医院内二科,福建南平353100

出　　处：《中国实用乡村医生杂志》2025年第1期21-24,28,共5页Chinese Practical Journal of Rural Doctor

摘　　要：目的探讨加味八珍汤辅助治疗乳腺癌术后化疗患者的效果及对骨髓抑制的影响。方法选取2022年2月—2023年1月在建瓯市中西医结合医院进行化疗的118例乳腺癌术后患者为研究对象,随机分为中西医组和西医组各59例。西医组采用盐酸表柔比星联合环磷酰胺化疗方案,中西医组在西医组化疗方案基础上采用加味八珍汤治疗。比较两组疗效以及化疗前后中医症候积分、血常规和肝功能指标。结果中西医组临床总有效率为96.61%,高于西医组的84.75%,差异有统计学意义(P<0.05)。化疗后,两组中医症候积分均低于化疗前,且化疗后中西医组中医症候积分低于西医组,差异有统计学意义(P<0.05)。化疗后,两组肝功能指标均高于化疗前,且化疗后中西医组肝功能指标低于西医组,差异有统计学意义(P<0.05)。化疗后,血常规指标中白细胞计数、中性粒细胞计数和血红蛋白水平,中西医组均高于化疗前、西医组均低于化疗前,且化疗后中西医组上述指标水平均高于西医组,差异均有统计学意义(P<0.05)。化疗后,两组血小板计数均低于化疗前,且化疗后中西医组血小板计数低于西医组,但差异均无统计学意义(P>0.05)。结论加味八珍汤辅助治疗乳腺癌术后化疗患者,具有较为理想的效果,能够进一步改善患者症状,预防骨髓抑制,且具有较好的安全性,值得推广使用。Objective To explore the effect of modified Bazhen decoction in adjuvant treatment of breast cancer patients undergoing postoperative chemotherapy and its influence on myelosuppression.Methods A total of 118 postoperative patients with breast cancer who received chemotherapy in Jian’ou Hospital of Integrated Traditional Chinese and Western Medicine from February 2022 to January 2023 were selected as the research objects,and were randomly divided into the Western medicine group and the Chinese and Western medicine group with 59 cases in each group.The Western medicine group used a combination chemotherapy regimen of epirubicin hydrochloride and cyclophosphamide,while the Chinese and Western medicine group treated with modified Bazhen decoction on the basis of the Western medicine group’s chemotherapy regimen.Compare the efficacy of two groups,as well as the Traditional Chinese Medicine(TCM)syndrome score,blood routine,and liver function indicators before and after chemotherapy.Results The total clinical effective rate of the Chinese and Western medicine group was 96.61%,which was significantly higher than the Western medicine group’s 84.75%(P<0.05).After chemotherapy,the TCM syndrome scores of both groups were lower than before chemotherapy,and the TCM syndrome scores of the Chinese and Western medicine groups were significantly lower than those of the Western medicine group after chemotherapy(P<0.05).After chemotherapy,the liver function indicators of both groups were higher than before chemotherapy,and the liver function indicators of the Chinese and Western medicine group were significantly lower than those of the Western medicine group after chemotherapy(P<0.05).After chemotherapy,the white blood cell count,neutrophil count,and hemoglobin levels were higher in the Chinese and Western medicine groups than before chemotherapy,and lower in the Western medicine group than before chemotherapy,and the levels of these above indicators in the Chinese and Western medicine groups were significantly higher than tho

关 键 词：乳腺癌 术后 化疗 骨髓抑制 加味八珍汤 疗效 

分 类 号：R737[医药卫生—肿瘤]