颅内动脉延长扩张与脑小血管病在急性脑梗死患者中的关系研究  

Study on the relationship between intracranial arterial elongation and dilation and cerebral small vessel disease in patients with acute cerebral infarction

作　　者：温骏 李淑芸[1] 林嘉辉 余瀛 WEN Jun;LI Shuyun;LIN Jiahui;YU Ying(Department of Neurology,Jiangmen Central Hospital,Guangdong,Jiangmen 529000,China)

机构地区：[1]广东省江门市中心医院神经内科,广东江门529000

出　　处：《中国医药科学》2025年第2期130-133,共4页China Medicine And Pharmacy

基　　金：广东省自然科学基金项目(2018A0303100009);广东省江门市科技计划项目(2021YL01075)。

摘　　要：目的探讨急性脑梗死患者中颅内动脉延长扩张与脑小血管病的关系。方法收集江门市中心医院神经内科2017年12月至2022年12月收治的413例急性脑梗死患者。根据影像学结果,分为颅内动脉延长扩张组与非颅内动脉延长扩张组,比较两组的临床特征,分析颅内动脉延长扩张与脑小血管病的关系。结果合并颅内动脉延长扩张患者58例(14.0%),颅内动脉延长扩张患者的平均年龄、高血压的比例明显高于非颅内动脉延长扩张患者,差异有统计学意义(P<0.05)。脑小血管病(近期皮层下小梗死、陈旧腔隙性梗死、白质高信号、血管周围间隙扩大、脑微出血)在颅内动脉延长扩张患者中的比例高于非颅内动脉延长扩张患者的比例,差异有统计学意义(P<0.05)。结论颅内动脉延长扩张在急性脑梗死患者中具有较高的发生率,颅内动脉延长扩张与脑小血管病有密切关系。Objective To explore the relationship between intracranial arterial elongation and dilation and cerebral small vessel disease in patients with acute cerebral infarction.Methods A total of 413 patients with acute cerebral infarction admitted to the Department of Neurology,Jiangmen Central Hospital from December 2017 to December 2022 were collected.According to the imaging results,the patients were divided into two groups:intracranial artery elongation and dilation group and non intracranial artery elongation and dilation group.The clinical characteristics of the two groups were compared,and the relationship between intracranial artery elongation and dilation and cerebral small vessel disease was analyzed.Results Among 58 patients(14.0%)with combined intracranial arterial elongation and dilation,the average age and proportion of hypertension in intracranial arterial elongation and dilation patients were significantly higher than those in non intracranial arterial elongation and dilation patients,and the difference was statistically significant(P<0.05).The proportion of cerebral small vessel disease(recent subcortical small infarction,old lacunar infarction,white matter hyperintensities,perivascular space enlargement,cerebral microbleeds)in patients with intracranial arterial elongation and dilation was higher than that in non intracranial arterial elongation and dilation patients,and the difference was statistically significant(P<0.05).Conclusion Intracranial arterial elongation and dilation have a high incidence in patients with acute cerebral infarction,and there is a close relationship between intracranial arterial elongation and dilation and cerebral small vessel disease.

关 键 词：颅内动脉延长扩张 脑小血管病 急性脑梗死 白质高信号 

分 类 号：R743.3[医药卫生—神经病学与精神病学]