动物源性食品中兽药残留检测技术及兽药残留污染状况分析  

Research progress on detection technology and analysis of veterinary drug residues in animal-derived foods

作　　者：余红伟 邓惠丹 杨华[2] 肖英平[2] 丁向英 吉小凤[2] YU Hongwei;DENG Huidan;YANG Hua;XIAO Yingping;DING Xiangying;JI Xiaofeng(Jiande Agriculture and Rural Bureau,Jiande 311600,Zhejiang,China;Institute of Agro-Product Safety and Nutrition,Zhejiang Academy of Agricultural Sciences,Hangzhou 310021,China;Jiangshan Livestock Development Service Center,Jiangshan 324100,Zhejiang,China)

机构地区：[1]建德市农业农村局,浙江建德311600 [2]浙江省农业科学院农产品质量安全与营养研究所,浙江杭州310021 [3]江山市养殖业发展服务中心,浙江江山324100

出　　处：《浙江农业学报》2025年第1期203-216,共14页Acta Agriculturae Zhejiangensis

基　　金：鸡蛋质量安全风险隐患排查评估与标准化建设(2022R19T80D15)。

摘　　要：随着经济社会不断发展,人们对日常饮食安全愈发重视,特别是动物源性食品中兽药残留问题受到人们的广泛关注。而兽药对畜牧渔业高质量发展发挥着重要作用,合理使用兽药可以预防或治疗养殖动物疾病、促进动物生产、提高饲料利用率、提高经济效益等,但兽药的不合理使用,很可能造成动物源性食品中兽药蓄积残留,并在食物链传递过程中被人体所吸收,对人们的饮食安全产生严重威胁。本文主要阐述了液液萃取、固相萃取、新型微萃取、QuEChERs、加速溶剂萃取、超临界流体萃取、微波辅助萃取等样品前处理方法,讨论了液相色谱技术、色谱-质谱联用技术、免疫学技术、生物传感器技术、光谱技术、分子生物学技术等检测技术,同时综述了动物源性食品中兽药残留现状,以期为后续动物源性食品中兽药残留分析和检测技术研发提供参考和借鉴。With the continuous development of economy and society,people pay more and more attention to the safety of daily diet,especially the safety problem of veterinary drug residues in animal-derived foods.Veterinary drugs play an important role in the high-quality development of animal husbandry and fishery.Rational use of veterinary drugs can prevent or treat diseases of cultured animals,promote animal production,improve feed utilization,improve economic benefits,etc.However,irrational use of veterinary drugs is likely to cause the accumulation of veterinary drugs in animal-derived foods and be absorbed by the human body in the process of food chain transmission.It poses a serious threat to people’s food safety.This paper mainly reviewed the research related to the analysis of veterinary drug residues in animal-derived foods,sample pretreatment methods such as liquid-liquid extraction,solid phase extraction,novel micro-extraction,QuEChERs,accelerated solvent extraction,supercritical fluid extraction,and microwave-assisted extraction,and detection techniques including liquid chromatography,chromatography-mass spectrometry,immunology,biosensor,spectroscopy and molecular biology.This study will be a good reference for future studies related to veterinary drug residue in animal-derived foods.

关 键 词：动物源性食品 兽药残留 前处理方法 检测技术 

分 类 号：S859.84[农业科学—临床兽医学]