基于3D Slicer软件的蝶鞍区三维重建技术对内镜下垂体瘤切除术患者创伤反应的影响  

Effect of three-dimensional reconstruction technology of sellar region based on 3D slicer software on traumatic respons in patients undergoing endoscopic pituitary tumor resection

作　　者：王磊[1] 邢振义[1] 郑杰[1] WANG Lei;XING Zhenyi;ZHENG Jie(Department of Neurosurgery,Xinxiang Central Hospital,Xinxiang,Henan 453000,China)

机构地区：[1]新乡市中心医院神经外科,河南新乡453000

出　　处：《现代医药卫生》2025年第2期350-353,共4页Journal of Modern Medicine & Health

基　　金：河南省医学科技攻关计划联合共建项目(LHGJ20191320)。

摘　　要：目的探讨在内镜下垂体瘤切除术中应用基于3D Slicer软件的蝶鞍区三维重建技术对患者创伤反应的影响。方法选取2022年1月至2024年1月该院收治的内镜下垂体瘤切除术患者75例,并随机分为对照组(37例)和观察组(38例)。对照组采用内镜下垂体瘤切除术,观察组在对照组基础上联合基于3D Slicer软件的蝶鞍区三维重建技术。比较2组术中出血量、手术时间、住院时间、术后并发症发生率,以及生长素(GH)、催乳素(PRL)、促甲状腺激素(TSH)、促肾上腺皮质激素(ACTH)、超敏C反应蛋白(hs-CRP)、皮质醇(Cor)、去甲肾上腺素(NE)水平。结果观察组手术时间、住院时间短于对照组,术中出血量小于对照组,差异有统计学意义(P<0.05)。2组术后并发症发生率比较,差异有统计学意义(P<0.05)。2组术前GH、PRL、TSH、ACTH水平比较,差异无统计学意义(P>0.05)。2组术后GH、PRL、TSH、ACTH水平低于术前,且观察组各指标低于对照组,差异有统计学意义(P<0.05)。2组术前hs-CRP、Cor、NE水平比较,差异无统计学意义(P>0.05)。观察组术后hs-CRP、Cor、NE水平低于对照组,差异有统计学意义(P<0.05)。结论在内镜下垂体瘤切除术中应用基于3D Slicer软件的蝶鞍区三维重建技术可提高手术效果,减少并发症,调节相关激素水平,同时也能减轻创伤反应。Objective To investigate the effect of three-dimensional reconstruction technology of sellar region based on 3D slicer software on patients′traumatic response in endoscopic pituitary tumor resection.Methods Seventy five patients who underwent endoscopic pituitary tumor resection in the hospital from January 2022 to January 2024 were selected and randomly divided into control group(37 cases)and observation group(38 cases).The control group was treated with endoscopic pituitary tumor resection,and the observation group was treated with three-dimensional reconstruction technology of sellar region based on 3D slicer software on the basis of the control group.The intraoperative blood loss,operation time,hospitalization time,incidence of postoperative complications,and the levels of growth hormone(GH),prolactin(PRL),thyroid stimulating hormone(TSH),adrenocorticotropic hormone(ACTH),high-sensitivity C-reactive protein(hs-CRP),cortisol(Cor)and norepinephrine(NE)were compared between the two groups.Results The operation time and hospitalization time of the observation group were shorter than those of the control group,and the intraoperative blood loss was less than that of the control group,the differences were statistically significant(P<0.05).There was significant difference in the incidence of postoperative complications between the two groups(P<0.05).There were no significant differences in preoperative GH,PRL,TSH,ACTH levels between the two groups(P>0.05).The levels of GH,PRL,TSH and ACTH in the two groups after operation were lower than those before operation,and the indexes in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).There were no significant differences in preoperative hs-CRP,Cor and NE levels between the two groups(P>0.05).The levels of hs-CRP,Cor and NE in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The application of three-dimensional reconst

关 键 词：三维重建技术 内镜 垂体瘤切除术 创伤反应 

分 类 号：R739.41[医药卫生—肿瘤]