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作 者:巢天闻 翟晓鑫 肖国民 CHAO Tianwen;ZHAI Xiaoxin;ZHANG Ddanyu;XIAO Guomin(Clinical Research Center,Hangzhou Combak Hospital,Hangzhou,Zhejiang 310024,China)
机构地区:[1]杭州康柏医院临床研究中心,浙江杭州310024
出 处:《现代医药卫生》2025年第2期518-521,共4页Journal of Modern Medicine & Health
摘 要:Ⅰ期药物临床试验集中采血时易发生血管迷走性晕厥。物理反压动作是血管迷走性晕厥现场急救的有效方法。该文分析了Ⅰ期药物临床试验中受试者易发生血管迷走性晕厥原因和目前现场急救现状,介绍了物理反压动作的作用及其机制及在Ⅰ期临床试验血管迷走性晕厥现场急救中的应用。以期促进该方法用于现场救护Ⅰ期临床试验血管迷走性晕厥受试者。Vasovagal syncope is easy to occur during the intensive blood collection in phase I drug clinical trials.Physical counter-pressure maneuvers Physical is an effective method for first aid of Vasovagal Syncope.This paper analyzed the reasons why subjects are prone to vasovagal syncope in phase I clinical trials and the current situation of on-site first aid,and introduced the function and mechanism of physical counter-pressure maneuvers and its application in on-site first aid of vasovagal syncope in phase I clinical trials in order to promote the application of this method in on-site rescue of the subjects with vasovagal syncope in phase I clinical trial.
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