腕踝针联合三阶梯镇痛法对晚期肺癌化疗患者癌痛程度及生活质量的影响  

Impact of wrist-ankle acupuncture combined with the three-step analgesic ladder on the degree of cancer pain and quality of life in patients with advanced lung cancer undergoing chemotherapy

作　　者：董芳芳 陆薇 李今 Dong Fang-fang;Lu wei;Li Jin(Department of Internal Medicine of Traditional Chinese Medicine,the First Affiliated Hospital of USTC(Anhui Provincial Hospital),Hefei,Anhui 230001,China;不详)

机构地区：[1]中国科学技术大学附属第一医院(安徽省立医院)中医内科,安徽合肥230001

出　　处：《慢性病学杂志》2024年第10期1462-1466,共5页Chronic Pathematology Journal

摘　　要：目的探究腕踝针联合三阶梯镇痛法对晚期肺癌化疗患者癌痛程度及生活质量的影响。方法选择2021年1月—2023年12月在安徽省立医院接受住院治疗的120例晚期肺癌化疗患者,运用随机数字表法分为对照组与研究组,各60例。对照组患者在基础治疗上加用三阶梯镇痛法,而研究组患者在对照组的治疗基础上加用腕踝针,比较两组患者在治疗后的临床治疗效果、免疫指标、癌痛程度、睡眠质量及生活质量情况。结果治疗后,两组患者的数字评分量表(numeric rating scale,NRS)评分降低(P<0.05),且研究组患者的NRS评分比对照组低(t=8.628,P<0.05)。治疗后,两组患者的CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)水平均提高,而CD8^(+)水平下降(P<0.05);相较于治疗后的对照组,研究组患者的CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)水平均较高(t=7.285、6.601、10.756,均P<0.05),且CD8^(+)水平较低(t=3.446,P<0.05)。治疗后,两组患者的生活质量各条目评分均升高(P<0.05),且研究组患者的认知功能、社会功能、角色功能、情绪功能评分较对照组高(t=3.153、5.685、5.865、5.282,均P<0.05);与同组治疗前比较,两组患者经治疗后的匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)评分均降低(P<0.05),且研究组患者的PSQI评分低于对照组(t=6.696,P<0.05)。研究组患者的治疗总缓解率(95.00%)高于对照组(83.33%)(χ^(2)=4.227,P=0.040)。研究组患者的不良发应发生率低于对照组,但差异无统计学意义(χ^(2)=3.003,P=0.083)。结论采用腕踝针联合三阶梯镇痛法治疗晚期肺癌化疗患者的疗效显著,能有效缓解疼痛,提高患者的机体免疫能力、睡眠质量以及生活质量水平,且安全性高。Objective To investigate the effects of wrist-ankle acupuncture combined with the three-step analgesic ladder on the degree of cancer pain and quality of life in patients with advanced lung cancer undergoing chemotherapy.Methods 120 patients with advanced lung cancer who were hospitalized and receiving chemotherapy at the Anhui Provincial Hospital from January 2021 to December 2023 were selected.Using a random number table method,they were divided into a control group and a study group,with 60 patients in each group.The control group received the three-step analgesic ladder in addition to basic treatment,while the study group received wrist-ankle acupuncture on top of the control group's treatment.Clinical treatment effects,immune indicators,cancer pain levels,sleep quality,and quality of life were compared between the two groups after treatment.Results After treatment,the numeric rating scale(NRS)scores of both groups decreased(P<0.05),and the NRS scores of the study group were lower than those of the control group(t=8.628,P<0.05).After treatment,the levels of CD3^(+),CD4^(+),and CD4^(+)/CD8^(+)increased in both groups,while CD8^(+)levels decreased(P<0.05).Compared with the control group after treatment,the study group had higher levels of CD3^(+),CD4^(+),and CD4^(+)/CD8^(+)(t=7.285,6.601,10.756,all P<0.05),and lower levels of CD8^(+)(t=3.446,P<0.05).After treatment,the quality of life scores for all items increased in both groups(P<0.05),and the scores of cognitive function,social function,role function and emotional function in the study group were higher than those in the control group(t=3.153,5.685,5.865,5.282,all P<0.05).Compared with before treatment in the same group,the Pittsburgh sleep quality index(PSQI)scores of both groups decreased after treatment(P<0.05),and the PSQI scores of the study group were lower than those of the control group(t=6.696,P<0.05).The overall response rate in the study group(95.00%)was higher than that in the control group(83.33%)(χ^(2)=4.227,P=0.040).The incidence of adverse r

关 键 词：晚期肺癌 三阶梯镇痛法 腕踝针 化疗 癌痛 生活质量 

分 类 号：R734.2[医药卫生—肿瘤] R47[医药卫生—临床医学]