Differential expression of plasma extracellular vesicle miRNAs as biomarkers for distinguishing psoriatic arthritis from psoriasis  

作　　者：Kexiang Yan Jie Zhu Mengmeng Zhang Fuxin Zhang Bing Wang Ling Han Qiong Huang Yulong Tang Yuan Li Nikhil Yawalkar Zhenghua Zhang Zhenmin Niu 

机构地区：[1]Department of Dermatology,Huashan Hospital,Fudan University,Shanghai 200040,China [2]State Key Laboratory of Genetic Engineering,Collaborative Innovation Center for Genetics and Development,School of Life Sciences,Human Phenome Institute,Fudan University,Shanghai 200438,China [3]Department of Dermatology,Inselspital,Bern University Hospital,University of Bern,Bern,CH-3012 Bern,Switzerland [4]Department of Genetics,Shanghai-MOST Key Laboratory of Health and Disease Genomics,Chinese National Human Genome Center at Shanghai(CHGC)and Shanghai Academy of Science&Technology(SAST),Shanghai 201203,China

出　　处：《Chinese Medical Journal》2025年第2期219-221,共3页中华医学杂志(英文版)

基　　金：funded by the National Key Research and Development Program of China(No.2023YFC2508100);the National Natural Science Foundation of China(Nos.81773322,82173420,81673054,81673073,and 81974471);the Shanghai Municipal Commission of Health and Family Planning(No.2023ZZ02018);the Shanghai Municipal Key Clinical Specialty(No.shslczdzk01002);the Natural Science Foundation of Shanghai(No.20ZR1440100);the Key Project in Basic Research Advocated by Shanghai Science and Technology Commission(No.13JC1402300);the Clinical Research Plan of SHDC(Nos.SHDC2020CR6022,SHDC2020CR1014B,SHDC22022302,and SHDC2024CRI052).

摘　　要：To the Editor:Psoriatic arthritis(PsA)affects up to 30%of patients with psoriasis,contributing to a decreased quality of life.PsA can involve a variety of clinical manifestations,including peripheral and axial arthritis,enthesitis,dactylitis,and nail disease.[1]Early intervention is important for preventing loss of function and permanent disability;however,the diagnosis of PsA is often delayed by an average of five years.[1]Therefore,it is important to identify biomarkers that can detect PsA in patients with psoriasis.

关 键 词：PSORIASIS identify biomarkers differential expression plasma extracellular vesicle psoriatic arthritis biomarkers 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]