帕金森病的诊断和治疗进展  

Advance in the diagnosis and treatment of Parkinson’s disease

作　　者：孙高慧[1] 冯美江[1] SUN Gaohui;FENG Meijiang(Department of Geriatrics,the Second Affiliated Hospital of Nanjing Medical University,Nanjing 210003,China)

机构地区：[1]南京医科大学第二附属医院老年医学科,江苏省南京市210003

出　　处：《实用老年医学》2025年第2期110-115,共6页Practical Geriatrics

基　　金：江苏省老年健康重点项目(LKZ2022004)。

摘　　要：PD是一种常见的神经退行性疾病,主要影响病人的运动功能,并伴随一系列非运动症状,严重影响病人的生活质量。随着人口老龄化的加剧,PD的发病率不断上升,其早期诊断和有效治疗的重要性愈发突出。近年来,针对PD的诊断和治疗方法取得了显著进展,特别是在早期诊断技术、药物治疗、手术治疗及新兴疗法方面。例如,影像学技术的进步使得早期识别PD成为可能,而新一代药物的问世则为病人提供了更多的治疗选择。此外,脑深部电刺激等手术治疗方法在改善运动症状上展现了良好的效果。本文将对这些进展进行综述,旨在为临床工作提供新的见解和启示。Parkinson’s disease(PD)is a common neurodegenerative disease that primarily affects the motor functions of patients and is accompanied by a range of non-motor symptoms,severely impacting the quality of life.With the aging population,the incidence of PD continues to rise,highlighting the importance of early diagnosis and effective treatment.In recent years,significant progress has been made in the diagnosis and treatment of PD,particularly in the development of early diagnostic techniques,pharmacological treatments,surgical interventions and emerging therapies.For example,advancements in imaging technology have made early identification of PD possible,while the emergence of new generation drugs has provided patients with more treatment options.Additionally,surgical treatments such as deep brain stimulation have shown good results in improving motor symptoms.This article will discuss these advancements,aiming to provide new insights and inspiration for clinical practice and promote the development of comprehensive management and treatment strategies for PD.

关 键 词：帕金森病 诊断 药物治疗 非药物治疗 

分 类 号：R742.5[医药卫生—神经病学与精神病学]