认知行为疗法结合正念心理干预对精神分裂症康复期青壮年男性患者的临床应用价值研究  

Effect of Cognitive Behavioral Therapy Combined with Mindfulness Psychological Intervention in Young Male Patients of Schizophrenia During Rehabilitation

作　　者：史振娟 梁学军 祝希泉 白晶 刘立志 段惠峰 Shi Zhenjuan;Liang Xuejun;Zhu Xiquan(The Whole Army Mental Disease Prevention and Control Institute,No.988 Hospital of Joint Logistic Support Force(Jiaozuo Yuan District),Jiaozuo,Henan,454000,China)

机构地区：[1]联勤保障部队第九八八医院(焦作院区)全军精神疾病防治研究所,河南焦作454000

出　　处：《黑龙江医学》2025年第3期259-261,265,共4页Heilongjiang Medical Journal

基　　金：河南省医学科技攻关计划联合共建项目(LHGJ20200791,LHGJ20210816,LHGJ20220906)。

摘　　要：目的:探索认知行为疗法结合正念心理干预对精神分裂症康复期青壮年男性患者心理韧性、糖脂代谢及精神症状的影响。方法:选取2020年1月—2022年12月联勤保障部队第九八八医院(焦作院区)收治的127例处于精神分裂症康复期的青壮年男性患者作为研究对象,根据随机数表法将其分为观察组(63例)和对照组(64例)。对照组采用常规治疗,观察组采用认知行为疗法结合正念心理干预。比较两组患者干预前后心理韧性量表、糖脂代谢、阳性与阴性症状量表(PANSS)情况。结果:干预后,观察组患者心理韧性量表各维度及总分均高于对照组,且各指标变化值(D值)高于对照组,差异均有统计学意义(t=12.502、28.019、22.731、35.102,P<0.05);观察组患者甘油三酯(TG)、总胆固醇(TC)、餐后2 h血糖(2 hPG)、空腹血糖(FPG)、糖化血红蛋白(HbA1c)水平均低于对照组,且各指标D值高于对照组,差异均有统计学意义(t=17.839、34.902、44.369、48.796、34.098,P<0.05);观察组患者PANSS各分量表评分及总分均低于对照组,且各指标D值高于对照组,差异均有统计学意义(t=23.844、51.735、89.654、42.614,P<0.05)。结论:对精神分裂症康复期青壮年男性患者实施认知行为疗法结合正念心理干预可提高其心理韧性,稳定机体糖脂代谢水平,进一步改善精神症状。Objective:To explore the effects of cognitive behavioral therapy combined with mindfulness psychological intervention on symptoms,glucose and lipid metabolism,and mental resilience in patients with schizophrenia during rehabilitation.Methods:Prospectively selecting 127 patients with schizophrenia during rehabilitation were admitted to treatment from January 2020 to December 2022.They were divided into 2 groups according to the random number table method.64 cases in the control group received conventional nursing care,and 63 cases in the observation group.Cognitive behavioral therapy combined with mindfulness psychological intervention was used to compare of the two groups self-esteem scale(SES)score,mental resilience scale score,total score of the positive and negative symptom scale(PANSS),and the level of glucose and lipid metabolism were compared.Results:After intervention,all dimensions and total scores of the mental toughness scale in the observation group were higher than those in the control group,and the change value of each index(D value)was higher than that in the control group,with statistically significant difference(t=12.502,28.019,22.731,35.102,P<0.05).The levels of triglyceride(TG),total cholesterol(TC),2 h postmeal blood glucose(2 hPG),fasting blood glucose(FPG)and glycated hemoglobin(HbA1c)in observation group were lower than those in control group,and the D value of each index was higher than that in control group.The difference was statistically significant(t=17.839,34.902,44.369,48.796,34.098;P<0.05).The scores and total scores of PANSS subscales in observation group were lower than those in control group,and the D values of each index were higher than those in control group,with statistically significant difference(t=23.844,51.735,89.654,42.614;P<0.05).Conclusion:Cognitive behavioral therapy combined with mindfulness psychological intervention for young men in the recovery period of schizophrenia can further improve mental symptoms,psychological resilience,and stabilize the level of glucose an

关 键 词：认知行为疗法 正念心理 精神分裂症 心理韧性 糖脂代谢 

分 类 号：R749.3[医药卫生—神经病学与精神病学]