基于肠道菌群探讨中医药治疗腹泻型肠易激综合征的研究进展  

Research progress of traditional Chinese medicine in treating diarrhoeal irritable bowel syndrome based on intestinal flora

作　　者：邹权 陈诺 杨晶晶 吴至久[1] ZOU Quan;CHEN Nuo;YANG Jingjing;WU Zhijiu(Department of Integrated Traditional Chinese and Western Medicine Proctology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China)

机构地区：[1]川北医学院附属医院中西医结合肛肠科,637000

出　　处：《天津医药》2025年第2期219-224,共6页Tianjin Medical Journal

基　　金：四川省中医药管理局课题(2020LC0099)。

摘　　要：肠易激综合征(IBS)是一种以腹痛、排便异常并伴有频率或粪便性状改变为主要临床症状的胃肠道功能紊乱疾病,以腹泻型肠易激综合征(IBS-D)最为多见。中医药疗法通过多成分、多靶点、多途径靶向调控肠道菌群治疗IBS-D取得了良好效果。该文立足肠道菌群,从肠道菌群与IBS-D的关系、中医对IBS-D及肠道菌群的认识、中医药疗法对肠道菌群的作用等方面进行综述。Irritable bowel syndrome(IBS)is a kind of gastrointestinal dysfunction disease characterized by abdominal pain and abnormal defecation accompanied by changes in frequency or fecal character as the main clinical symptoms,and diarrhea-type irritable bowel syndrome(IBS-D)is the most common.It has been found that Chinese medicine therapy has achieved good results in the treatment of IBS-D through multi-component,multi-target and multi-pathway targeted regulation of intestinal flora.Therefore,based on intestinal flora,this paper reviews the relationship between intestinal flora and IBS-D,the understanding of Chinese medicine on IBS-D and intestinal flora,and the role of Chinese medicine therapy on intestinal flora.

关 键 词：肠易激综合征 腹泻 胃肠道微生物组 中医药疗法 

分 类 号：R574.62[医药卫生—消化系统] R28[医药卫生—内科学]