IMH患者黄斑区血管和血流变化及其与视力预后关系的研究进展  

Advances of vascular and blood flow changes in macular area and their relationship with visual prognosis in patients with idiopathic macular hole

作　　者：张佳璇(综述) 王琪 肖迎(审校) Zhang Jiaxuan;Wang Qi;Xiao Ying(Department of Ophthalmology,Shandong Provincial Hospital Affiliated to the First Medical University of Shandong Province,Jinan 250021,China)

机构地区：[1]山东第一医科大学附属省立医院眼科,济南250021

出　　处：《中华实验眼科杂志》2025年第2期186-192,共7页Chinese Journal Of Experimental Ophthalmology

基　　金：山东省自然科学基金(ZR2022MH280);山东省医药卫生科技项目(202307020692);山东省医药卫生科技发展计划(2017WS469)。

摘　　要：近年来,随着微创玻璃体视网膜手术技术的发展,特发性黄斑裂孔(IMH)的闭合率得到极大提高,但视力恢复却不尽如人意。研究表明,黄斑区视网膜血管连续性变化、视网膜与脉络膜血流灌注改变均参与IMH的形成及愈合过程,并可能对IMH患者视力预后产生明显影响。本文将对IMH患眼及对侧眼黄斑区视网膜、脉络膜血管的重要参数变化及其与视力预后的关系进行综述,分别讨论中心凹无血管区、浅层和深层毛细血管丛密度、周围囊腔以及IMH闭合前后视网膜血管位置变化与黄斑区视网膜血流灌注及视力预后的关系,并总结IMH患者脉络膜血流灌注变化及不同手术方式对黄斑区血流灌注影响的相关研究结果,为进一步深入了解IMH的病因及预后提供依据。In recent years,idiopathic macular hole(IMH)surgery has a very high success rate due to the development of small-gauge vitrectomy,while the recovery of visual acuity is not satisfactory.Current studies have found that continuity of retinal blood vessels in the macular area and changes in retinal and choroidal perfusion are closely related to the formation and healing of MH,and have a significant impact on the visual prognosis in IMH patients.This article reviews the research progress on variations of parameters for retinal and choroidal vessels in IMH patients,as well as their relationship with visual prognosis.For retinal parameters,the changes in the foveal avascular zone,superficial and deep capillary plexus density,paracentral intraretinal cystoid spaces,retinal vessels position are discussed.Relevant research related to choroidal blood flow perfusion changes and the effects of different surgical methods on macular perfusion in patients with IMH are summarized to provide basis for further understanding the etiology and prognosis of IMH.

关 键 词：黄斑裂孔 特发性 体层摄影术 光学相干 视力 综述 

分 类 号：R779.6[医药卫生—眼科]