比较胸腔镜和开胸肺叶切除术治疗非小细胞肺癌的临床价值  

Comparison on the clinical value of thoracoscopic and open lobectomy in the treatment of non-small cell lung cancer

作　　者：廉士海[1] LIAN Shi-hai(Outpatient Department,Zaozhuang Municipal Hospital,Zaozhuang 277100,China)

机构地区：[1]枣庄市立医院门诊部,277100

出　　处：《中国现代药物应用》2025年第2期26-29,共4页Chinese Journal of Modern Drug Application

摘　　要：目的 评价对非小细胞肺癌患者予以胸腔镜和开胸肺叶切除术治疗的效果。方法 选择66例非小细胞肺癌患者,根据双盲法分为开胸组与胸腔镜组,每组33例。开胸组提供开胸肺叶切除术治疗,胸腔镜组提供胸腔镜肺叶切除术治疗。对比两组患者的手术情况、并发症发生率及肺功能指标。结果 胸腔镜组的手术切口长度(2.11±0.56)cm、术后下床时间(15.27±3.23)h、术后拔管时间(2.15±0.56)d、住院时间(4.13±0.98)d短于开胸组的(10.27±2.67)cm、(35.63±4.51)h、(3.76±0.89)d、(7.22±2.64)d,术中出血量(113.73±28.98)ml少于开胸组的(322.17±32.38)ml,具有统计学意义(P<0.05)。胸腔镜组并发症发生率6.06%低于开胸组的30.30%,具有统计学意义(P<0.05)。术后,与同组术前相比,两组的用力肺活量、第1秒用力呼气容积、每分钟通气量均显著提高,且胸腔镜组的用力肺活量(3.61±0.67)L、第1秒用力呼气容积(2.93±0.38)L、每分钟通气量(6.42±0.72)L/min高于开胸组的(2.83±0.76)L、(2.65±0.49)L、(5.89±0.87)L/min,具有统计学意义(P<0.05)。结论 非小细胞肺癌应用胸腔镜肺叶切除术治疗的效果更佳,可以降低创伤和并发症发生率,改善肺功能的恢复情况,值得推广。To evaluate the effect of thoracoscopic and open lobectomy in the treatment of non-small cell lung cancer.Methods 66 patients with non-small cell lung cancer were selected and divided into thoracotomy group and thoracoscopic group according to double-blind method,each consisting of 33 patients.The thoracotomy group was given open lobectomy,and the thoracoscopic group was given thoracoscopic lobectomy.The clinical efficacy of the two groups of patients was compared.The surgical outcomes,incidence of complications,and lung function indicators were compared between the two groups.Results In the thoracoscopic group,the incision length was(2.11±0.56) cm,the postoperative ambulation time was(15.27±3.23) h,the extubation time was(2.15±0.56) d,and the hospitalization time was(4.13±0.98) d,which were shorter than(10.27±2.67) cm,(35.63±4.51) h,(3.76±0.89) d,and(7.22±2.64) d in the thoracotomy group;the intraoperative blood loss of(113.73±28.98) ml in the thoracoscopic group was less than(322.17±32.38) ml in the thoracotomy group;there was a statistical significance(P<0.05).The incidence of complications of 6.06% in the thoracoscopic group was lower than 30.30% in the thoracotomy group,and there was a statistical significance(P<0.05).After operation,the forced vital capacity,forced expiratory volume in one second and minute ventilation volume in both groups were significantly higher than those before operation in this group;in the thoracotomy group,the forced vital capacity was(3.61±0.67) L,the forced expiratory volume in one second was(2.93±0.38) L and the minute ventilation volume was(6.42±0.72) L/min,which were higher than(2.83±0.76) L,(2.65±0.49) L and(5.89±0.87) L/min in the thoracotomy group;there was a statistical significance(P<0.05).Conclusion The treatment effect of thoracoscopic lobectomy for non-small cell lung cancer is better,which can reduce trauma and incidence of complications and improve the recovery of lung function,and is worth popularizing.

关 键 词：胸腔镜 开胸 肺叶切除术 非小细胞肺癌 并发症 肺功能 

分 类 号：R734.2[医药卫生—肿瘤]