重性精神疾病妊娠期及哺乳期用药与管理  

Medication and management for patients with severe mental illness during pregnancy and lactation

作　　者：廖腊梅 冯浩轲 柳绪珍[2] 孙静[2] LIAO La-mei;FENG Hao-ke;LIU Xu-zhen;SUN Jing(Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学,210029 [2]南京医科大学附属脑科医院精神一科

出　　处：《临床精神医学杂志》2025年第1期72-76,共5页Journal of Clinical Psychiatry

基　　金：南京市卫生科技发展项目YKK22141。

摘　　要：精神分裂症、双相障碍等是临床常见的重性精神障碍,这些疾病大多需要长期治疗。对于患有重性精神障碍的女性,在妊娠和哺乳期间的用药决策,直接关系到母亲、胎儿和婴儿的短期和长期身心健康。该时期治疗涉及伦理和安全问题,相关研究匮乏且多为小样本或个案报道。本文就近年来妊娠期与哺乳期治疗相关报道进行综述,以期安全管理重性精神患者的妊娠期与哺乳期。Schizophrenia and bipolar disorder,etc.are common serious mental disorders,most of which require longterm treatment.Female patients in their gestational age are likely to face some important choices for the treatment during pregnancy and lactation.Medication treatment or not is associated with the shortterm and longterm physical and mental health issue for the fetuses,infants and pregnant women.Related researches are mostly inadequate with small samples or case reports because of treatment in the period involved ethical and safety problems.This review will focus on the treatment researches and reports published in recent years to help clinician to safely manage patients with severe mental illness during pregnancy and lactation.

关 键 词：重性精神疾病 妊娠期 哺乳期 精神药物 安全性 

分 类 号：R749.3[医药卫生—神经病学与精神病学]