AI empowers exploration of protein universe  

作　　者：Wuke Wang Xingxu Huang 

机构地区：[1]Zhejiang Provincial Key Laboratory of Pancreatic Disease,The First Affiliated Hospital,and Institute of Translational Medicine,Zhejiang University School of Medicine,Hangzhou 310029,China

出　　处：《Science China(Life Sciences)》2025年第2期588-589,共2页中国科学(生命科学英文版)

基　　金：supported by the National Key R&D Program of China(2021YFA0804702)。

摘　　要：Deaminases which perform the function of converting cytosine to thymine are ubiquitous in nature with over 120,000 known variants,each exhibiting significant differences.However,gene editing technologies have remarkably revealed that these deaminases share similar functions.Historically,the mining of novel proteins has been conducted through sequence alignment and the categorization of conserved regions to identify functional modules within protein sequences.

关 键 词：FUNCTIONS POWERS ALIGNMENT 

分 类 号：TP18[自动化与计算机技术—控制理论与控制工程] Q51[自动化与计算机技术—控制科学与工程]