消化内镜联合病理活检在慢性萎缩性胃炎肠上皮化生程度、病理类型诊断中的应用  

Application of digestive endoscopy combined with pathological biopsy in the diagnosis of intestinal metaplasia degree and pathological type of chronic atrophic gastritis

作　　者：颜岩 弋龙江 宗亮亮 Yan Yan;Yi Long-jiang;Zong Liang-liang(Department of Gastroenterology,Ruzhou First People's Hospital,Ruzhou 467500,Henan,China)

机构地区：[1]汝州市第一人民医院消化内科,河南汝州467500

出　　处：《四川生理科学杂志》2025年第2期386-388,共3页

摘　　要：目的:评估消化内镜联合病理活检在诊断慢性萎缩性胃炎肠上皮化生程度及病理类型中的价值。方法:选取2021年3月至2024年3月在本院消化内科就诊的82例慢性萎缩性胃炎患者,均接受病理活检和消化内镜检查。对比并分析两种检查方法的诊断结果,绘制接受者操作特性(Receiver operating characteristic curve,ROC)ROC曲线,分析联合诊断在慢性萎缩性胃炎肠上皮化生程度、病理类型的诊断价值。结果:不同肠上皮化生程度的胃黏膜皱襞、血管透见及肠上皮化生表现比较,差异具有统计学意义(P<0.05)。消化内镜联合病理活检诊断慢性萎缩性胃炎肠上皮化生程度的曲线下面积(Area Under Curve,AUC)(95%CI)、敏感度及特异度分别为0.950(0.900-1.000)、95.24%、95.37%,显著高于消化内镜或病理活检单独诊断效果(P<0.05)。联合诊断在区分慢性萎缩性胃炎病理类型方面AUC(95%CI)、敏感度及特异度分别为0.982(0.953-1.000)、95.96%、98.34%,显著高于单独诊断。结论:消化内镜联合病理活检在慢性萎缩性胃炎肠上皮化生程度及病理类型诊断中具有重要的应用价值,可提高诊断的准确性和可靠性,减少漏诊和误诊的情况。Objective:To evaluate the value of digestive endoscopy combined with pathological biopsy in the diagnosis of intestinal metaplasia and pathological types of chronic atrophic gastritis.Methods:From March 2021 to March 2024,82 patients with chronic atrophic gastritis who were treated in the Department of Gastroenterology of our hospital were selected.The diagnostic results of the two methods were compared and analyzed,and the receiver operating characteristic curve(ROC)ROC curve was drawn to analyze the diagnostic value of the combined diagnosis in the degree of intestinal metaplasia and pathological type of chronic atrophic gastritis.Results:There were statistically significant differences in gastric mucosal folds,vascular penetration and intestinal metaplasia among different degrees of intestinal metaplasia(P<0.05).The area under the curve(AUC)(95%CI),sensitivity and specificity of digestive endoscopy combined with pathological biopsy in the diagnosis of intestinal metaplasia in chronic atrophic gastritis were 0.950(0.900-1.000),95.24%and 95.37%,respectively,which were significantly higher than those of digestive endoscopy or pathological biopsy alone(P<0.05).The AUC(95%CI),sensitivity and specificity of combined diagnosis in distinguishing pathological types of chronic atrophic gastritis were 0.982(0.953-1.000),95.96%and 98.34%,respectively,which were significantly higher than those of single diagnosis.Conclusion:Digestive endoscopy combined with pathological biopsy has important application value in the diagnosis of intestinal metaplasia degree and pathological types of chronic atrophic gastritis,which can improve the accuracy and reliability of diagnosis and reduce the cases of missed diagnosis and misdiagnosis.

关 键 词：消化内镜 病理活检 慢性萎缩性胃炎 肠上皮化生程度 病理类型 

分 类 号：R573.3[医药卫生—消化系统]