在神经成像研究中意外发现的伦理讨论  

Ethical Discussion of Incidental Findings in Neuroimaging Studies

作　　者：冯龙飞[1] FENG Longfei(Aesthetic Medical School,Yichun Uni-versity,Yichun 336000,China)

机构地区：[1]宜春学院美容医学院,江西宜春336000

出　　处：《医学与哲学》2025年第2期12-16,共5页Medicine and Philosophy

基　　金：2022年江西省社科规划项目(22ZX05);2022年江西省学位与研究生教育教学改革研究项目(JXYJG-2022-194)。

摘　　要：在神经成像技术研究过程中,如果产生的意外发现能给研究参与者带来明显医疗帮助,且已获得其知情同意的情况下,研究人员应告知其意外发现。对此,通过互惠原则、利他原则和轻松救助理论可以对其提供伦理辩护。除此之外,通过轻松救助理论论证了研究人员应承担适度寻找意外发现的道德责任,但需权衡研究方案的成本和效益。最后,文章提出了意外发现的分类和具体反馈计划,以确保研究参与者能及时获得对健康有重要影响的发现。但是,划定意外发现的范围颇具挑战,需综合考虑意外发现的科学有效性、临床意义和可操作性等因素。During neuroimaging research,if the incidental findings can bring significant medical benefits to the research participants and their informed consent has been obtained,researchers should inform them of the incidental findings.This obligation can be ethically justified through the principles of reciprocity,altruism,and the easy rescue theory.In addition,the easy rescue theory suggests that researchers bear a moral responsibility to make reasonable efforts to identify incidental findings,while balancing the cost and benefit of the research protocol.This paper also proposes the classification of incidental findings and specific feedback plans to ensure that research participants receive timely information about discoveries that may significantly impact their health.However,defining the scope of incidental findings is quite challenging and requires a comprehensive consideration of factors such as the scientific validity,clinical significance,and practical feasibility.

关 键 词：神经成像研究 意外发现 伦理论证 告知义务 

分 类 号：R-05[医药卫生]